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CUR61414

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For Research Use Only | Not For Clinical Use
CATAP334998366
CAS334998-36-6
Structure
Molecular Weight550.69
InChI KeyWPHXYKUPFJRJDK-AZGAKELHSA-N
Description≥98% (HPLC)
SolubilityDMSO: 2 mg/mL (clear solution, warmed)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Discovery, Molecular and Pharmacological Characterization of GSA-10, a Novel Small-Molecule Positive Modulator of Smoothened

Tatiana Gorojankina, Lucile Hoch, Hélène Faure, Hermine Roudaut, Elisabeth Traiffort, Angèle Schoenfelder, Nicolas Girard, André Mann, Fabrizio Manetti, Antonio Solinas, Elena Petricci, Maurizio Taddei, etc.

Mol Pharmacol. 2013 May;83(5):1020-9.

PMID: 23448715

1

Hedgehog Signaling Pathway and Gastric Cancer

Yuriko Katoh, Masaru Katoh

Cancer Biol Ther. 2005 Oct;4(10):1050-4.

PMID: 16258256

1

Identification of a Small Molecule Inhibitor of the Hedgehog Signaling Pathway: Effects on Basal Cell Carcinoma-Like Lesions

Juliet A Williams, Oivin M Guicherit, Beatrice I Zaharian, Yin Xu, Ling Chai, Hynek Wichterle, Charlene Kon, Christine Gatchalian, Jeffery A Porter, Lee L Rubin, Frank Y Wang

Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4616-21.

PMID: 12679522

1

Targeting Superficial or Nodular Basal Cell Carcinoma With Topically Formulated Small Molecule Inhibitor of Smoothened

Tracy Tang, Jean Y Tang, Dongwei Li, Mike Reich, Christopher A Callahan, Ling Fu, Robert L Yauch, Frank Wang, Karen Kotkow, Kris S Chang, Elana Shpall, Angela Wu, Lee L Rubin, James C Marsters Jr, Ervin H Epstein Jr, etc.

Clin Cancer Res. 2011 May 15;17(10):3378-87.

PMID: 21558397

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