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CXCR3 Agonist, PS372424

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For Research Use Only | Not For Clinical Use
CATIAR4249357
Molecular Weight588.74
DescriptionThe CXCR3 Agonist, PS372424 controls the biological activity of CXCR3. This small molecule/inhibitor is primarily used for Cell Signaling applications.
SolubilityDMSO: 100 mg/mL
Assay≥97% (HPLC)
Colorwhite
Formpowder; protect from light
Size5MG
Storage Conditions+2C to +8C
1

Biased Agonists of the Chemokine Receptor CXCR3 Differentially Control Chemotaxis and Inflammation

Jeffrey S Smith, Lowell T Nicholson, Jutamas Suwanpradid, Rachel A Glenn, Nicole M Knape, Priya Alagesan, Jaimee N Gundry, Thomas S Wehrman, Amber Reck Atwater, Michael D Gunn, Amanda S MacLeod, Sudarshan Rajagopal

Sci Signal. 2018 Nov 6;11(555):eaaq1075.

PMID: 30401786

1

Chemokine Receptor CXCR3 Agonist Prevents Human T-cell Migration in a Humanized Model of Arthritic Inflammation

Graeme O'Boyle, Christopher R J Fox, Hannah R Walden, Joseph D P Willet, Emily R Mavin, Dominic W Hine, Jeremy M Palmer, Catriona E Barker, Christopher A Lamb, Simi Ali, John A Kirby

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4598-603.

PMID: 22392992

1

Differential Activation of Hepatic Invariant NKT Cell Subsets Plays a Key Role in Progression of Nonalcoholic Steatohepatitis

Igor Maricic, Idania Marrero, Akiko Eguchi, Ryota Nakamura, Casey D Johnson, Suryasarathi Dasgupta, Carolyn D Hernandez, Phirum Sam Nguyen, Austin D Swafford, Rob Knight, Ariel E Feldstein, Rohit Loomba, etc.

J Immunol. 2018 Nov 15;201(10):3017-3035.

PMID: 30322964

1

Evidence for PI3K-dependent CXCR3 Agonist-Induced Degranulation of Human Cord Blood-Derived Mast Cells

Ian Willox, Irina Mirkina, John Westwick, Stephen G Ward

Mol Immunol. 2010 Aug;47(14):2367-77.

PMID: 20627397

1

The Role of CXCR3/LRP1 Cross-Talk in the Invasion of Primary Brain Tumors

Kevin Boyé, Nadège Pujol, Isabel D Alves, Ya-Ping Chen, Thomas Daubon, Yi-Zong Lee, Stephane Dedieu, Marion Constantin, Lorenzo Bello, Marco Rossi, Rolf Bjerkvig, Shih-Che Sue, Andreas Bikfalvi, Clotilde Billottet

Nat Commun. 2017 Nov 17;8(1):1571.

PMID: 29146996

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