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CXCR4 Antagonist III

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For Research Use Only | Not For Clinical Use
CATIAR4249393
Molecular Weight501.71
DescriptionThe CXCR4 Antagonist III controls the biological activity of CXCR4. This small molecule/inhibitor is primarily used for Biochemicals applications.
SolubilityDMSO: 25 mg/mL; water: 25 mg/mL
Assay≥98% (HPLC)
Colorwhite
Formsolid; desiccated; protect from light
Size10MG
Storage Conditions+2C to +8C
1

A Head-To-Head Phase III Study Comparing Zanubrutinib Versus Ibrutinib in Patients With Waldenström Macroglobulinemia

Constantine S Tam, Veronique LeBlond, William Novotny, Roger G Owen, Alessandra Tedeschi, Siminder Atwal, Aileen Cohen, Jane Huang, Christian Buske

Future Oncol. 2018 Sep;14(22):2229-2237.

PMID: 29869556

1

Characterization, Dynamics, and Mechanism of CXCR4 Antagonists on a Constitutively Active Mutant

Eric M Rosenberg Jr, Reed E S Harrison, Lun Kelvin Tsou, Natalie Drucker, Brock Humphries, Deepa Rajasekaran, Kathryn E Luker, Chien-Huang Wu, Jen-Shin Song, Chuan-Jen Wang, James W Murphy, Yung-Chi Cheng, etc.

Cell Chem Biol. 2019 May 16;26(5):662-673.e7.

PMID: 30827936

1

Clinical Significance of Chemokine Receptor Antagonists

Miao Miao, Erik De Clercq, Guangdi Li

Expert Opin Drug Metab Toxicol. 2020 Jan;16(1):11-30.

PMID: 31903790

1

CXCL12 and CXCR7 Are Relevant Targets to Reverse Cell Adhesion-Mediated Drug Resistance in Multiple Myeloma

Johannes M Waldschmidt, Anna Simon, Dagmar Wider, Stefan J Müller, Marie Follo, Gabriele Ihorst, Sarah Decker, Joschka Lorenz, Manik Chatterjee, Abdel K Azab, Justus Duyster, Ralph Wäsch, Monika Engelhardt

Br J Haematol. 2017 Oct;179(1):36-49.

PMID: 28670693

1

Phase I/II Trial of the CXCR4 Inhibitor Plerixafor in Combination With Bortezomib as a Chemosensitization Strategy in relapsed/refractory Multiple Myeloma

Irene M Ghobrial, Chia-Jen Liu, Oksana Zavidij, Abdel K Azab, Rachid Baz, Jacob P Laubach, Yuji Mishima, Philippe Armand, Nikhil C Munshi, Frank Basile, Michael Constantine, James Vredenburgh, Adam Boruchov, etc.

Am J Hematol. 2019 Nov;94(11):1244-1253.

PMID: 31456261

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