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CyPPA

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For Research Use Only | Not For Clinical Use
CATAP73029739
CAS73029-73-9
Structure
MDL NumberMFCD01550586
Molecular Weight285.39
InChI KeyUSEMRPYUFJNFQN-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: >10 mg/mL; H2O: <2 mg/mL
Assay≥98% (HPLC)
Colorwhite
Formsolid
Size5MG, 25MG
Storage Conditions2-8°C
1

Activation of KCNN3/SK3/K(Ca)2.3 Channels Attenuates Enhanced Calcium Influx and Inflammatory Cytokine Production in Activated Microglia

Amalia M Dolga, Till Letsche, Maike Gold, Nunzianna Doti, Michael Bacher, Nipavan Chiamvimonvat, Richard Dodel, Carsten Culmsee

Glia. 2012 Dec;60(12):2050-64.

PMID: 23002008

1

Concomitant SK Current Activation and Sodium Current Inhibition Cause J Wave Syndrome

Mu Chen, Dong-Zhu Xu, Adonis Z Wu, Shuai Guo, Juyi Wan, Dechun Yin, Shien-Fong Lin, Zhenhui Chen, Michael Rubart-von der Lohe, Thomas H Everett 4th, Zhilin Qu, James N Weiss, Peng-Sheng Chen

JCI Insight. 2018 Nov 15;3(22):e122329.

PMID: 30429367

1

Diadenosine Tetraphosphate Activates P2Y

Andrea Paquola, Noemi Mañé, Maria Cecilia Giron, Marcel Jimenez

Eur J Pharmacol. 2019 Jul 15;855:160-166.

PMID: 31063775

1

SK Channel Enhancers Attenuate Ca2+-dependent Arrhythmia in Hypertrophic Hearts by Regulating mito-ROS-dependent Oxidation and Activity of RyR

Tae Yun Kim, Radmila Terentyeva, Karim H F Roder, Weiyan Li, Man Liu, Ian Greener, Shanna Hamilton, Iuliia Polina, Kevin R Murphy, Richard T Clements, Samuel C Dudley Jr, Gideon Koren, Bum-Rak Choi, Dmitry Terentyev

Cardiovasc Res. 2017 Mar 1;113(3):343-353.

PMID: 28096168

1

The Ion Channel Activator CyPPA Inhibits Melanogenesis via the GSK3β/β-catenin Pathway

Tai Kyung Noh, Seung Hyun Bang, Ye Jin Lee, Hong Il Cho, Mi Young Jung, Inki Kim, Chae Hun Leem, Sung Eun Chang

Chem Biol Interact. 2019 Feb 25;300:1-7.

PMID: 30597128

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