D-(-)-2-Amino-5-phosphonopentanoic Acid - CAS 79055-68-8

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For Research Use Only | Not For Clinical Use

CAT	AP79055688-B
CAS	79055-68-8
Structure
Molecular Weight	197.13

Description	Active enantiomer of DL-2-amino-5-phosphonopentanoic acid (AP5) that is a commonly used as a competitive NMDA receptor antagonist.
Solubility	dilute aqueous base: 1 mg/mL; water: 1 mg/mL
Assay	≥97% (HPLC)
Color	white
Form	solid; desiccated; protect from light
Size	5MG
Storage Conditions	+2C to +8C

Effect of D-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic Acid on Focal Cerebral Ischemia in Cat

M Okada, H Ueda, M Kometani, K Nakao

Arzneimittelforschung. 1997 Jun;47(6):703-5.

PMID: 9239446

Effect of D-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic Acid on Ischemic Brain Damage Induced by Four-Vessel Occlusion in Rats

M Okada, Y Fujimura, H Ueda, M Kometani, K Nakao, T Inukai

Arzneimittelforschung. 1997 Feb;47(2):115-9.

PMID: 9079228

Effects of the Competitive N-methyl-D-aspartate Antagonist CGP 37849 and Its Ethylester CGP 39551 on N-methyl-D-aspartate-evoked Whole-Cell Currents in Cultured Spinal Neurones and on Vestibular Stimulation-Induced Seizures in EL Mice

R D'Hooge, A Raes, M Hiramatsu, A Mori, P P Van Bogaert, P P De Deyn

Arzneimittelforschung. 1998 Dec;48(12):1121-5.

PMID: 9893924

Neuroprotective Effect of D-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic Acid in the Gerbil Model of Transient Global Cerebral Ischemia

M Okada, H Ueda, M Kometani, K Nakao, Y Kohjimoto, I Takahashi, I Tanaka

Arzneimittelforschung. 1997 Jun;47(6):700-2.

PMID: 9239445

NMDA Receptor Antagonists Impair Motor Performance in Immature Rats

A Mikulecká, P Mares

Psychopharmacology (Berl). 2002 Aug;162(4):364-72.

PMID: 12172689