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D3T

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For Research Use Only | Not For Clinical Use
CATIAR4242978
Molecular Weight134.24
EC Number208-595-0
Description≥98% (NMR)
SolubilityDMSO: ≥10 mg/mL
Assay≥98% (NMR)
Formsolid
Size5MG, 25MG
Storage Conditions2-8°C
1

3H-1,2-dithiole-3-thione as a Novel Therapeutic Agent for the Treatment of Experimental Autoimmune Encephalomyelitis

Ping-Chang Kuo, Dennis A Brown, Barbara A Scofield, I-Chen Yu, Fen-Lei Chang, Pei-Yu Wang, Jui-Hung Yen

Brain Behav Immun. 2016 Oct;57:173-186.

PMID: 27013356

1

3H-1,2-Dithiole-3-thione as a Novel Therapeutic Agent for the Treatment of Ischemic Stroke Through Nrf2 Defense Pathway

Ping-Chang Kuo, I-Chen Yu, Barbara A Scofield, Dennis A Brown, Eric T Curfman, Hallel C Paraiso, Fen-Lei Chang, Jui-Hung Yen

Brain Behav Immun. 2017 May;62:180-192.

PMID: 28132764

1

3H-1,2-dithiole-3-thione Protects Retinal Pigment Epithelium Cells Against Ultra-violet Radiation via Activation of Akt-mTORC1-dependent Nrf2-HO-1 Signaling

Ke-Ran Li, Su-Qing Yang, Yi-Qing Gong, Hong Yang, Xiu-Miao Li, Yu-Xia Zhao, Jin Yao, Qin Jiang, Cong Cao

Sci Rep. 2016 May 6;6:25525.

PMID: 27151674

1

Pharmacological Activation of the Nrf2 Pathway by 3H-1, 2-dithiole-3-thione Is Neuroprotective in a Mouse Model of Alzheimer Disease

YuanBo Cui, ShanShan Ma, ChunYan Zhang, DongPeng Li, Bo Yang, PengJu Lv, Qu Xing, Tuanjie Huang, Greta Luyuan Yang, Wei Cao, FangXia Guan

Behav Brain Res. 2018 Jan 15;336:219-226.

PMID: 28887195

1

Stabilization of Nrf2 Protein by D3T Provides Protection Against Ethanol-Induced Apoptosis in PC12 Cells

Jian Dong, Dong Yan, Shao-Yu Chen

PLoS One. 2011 Feb 3;6(2):e16845.

PMID: 21304811

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