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DBeQ

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For Research Use Only | Not For Clinical Use
CATIAR4242996
MDL NumberMFCD03691820
Molecular Weight340.42
InChI KeyQAIMUUJJAJBPCL-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥20 mg/mL
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditionsroom temp
1

Dendrimer-Based Selective Proteostasis-Inhibition Strategy to Control NSCLC Growth and Progression

Kyla Walworth, Manish Bodas, Ryan John Campbell, Doug Swanson, Ajit Sharma, Neeraj Vij

PLoS One. 2016 Jul 19;11(7):e0158507.

PMID: 27434122

1

Development of p97 AAA ATPase Inhibitors

Tsui-Fen Chou, Raymond J Deshaies

Autophagy. 2011 Sep;7(9):1091-2.

PMID: 21606684

1

Novel p97/VCP Inhibitor Induces Endoplasmic Reticulum Stress and Apoptosis in Both Bortezomib-Sensitive and -Resistant Multiple Myeloma Cells

Nao Nishimura, Mohamed O Radwan, Masayuki Amano, Shinya Endo, Eri Fujii, Hironori Hayashi, Shikiko Ueno, Niina Ueno, Hiro Tatetsu, Hiroyuki Hata, Yoshinari Okamoto, Masami Otsuka, Hiroaki Mitsuya, Masao Matsuoka, etc.

Cancer Sci. 2019 Oct;110(10):3275-3287.

PMID: 31368616

1

Reversible Inhibitor of p97, DBeQ, Impairs Both Ubiquitin-Dependent and Autophagic Protein Clearance Pathways

Tsui-Fen Chou, Steve J Brown, Dmitriy Minond, Brian E Nordin, Kelin Li, Amanda C Jones, Peter Chase, Patrick R Porubsky, Brian M Stoltz, Frank J Schoenen, Matthew P Patricelli, Peter Hodder, Hugh Rosen, etc.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4834-9.

PMID: 21383145

1

The AAA ATPase Vps4 Plays Important Roles in Candida Albicans Hyphal Formation and Is Inhibited by DBeQ

Yahui Zhang, Wanjie Li, Mi Chu, Hengye Chen, Haoyuan Yu, Chaoguang Fang, Ningze Sun, Qiming Wang, Tian Luo, Kaiju Luo, Xueping She, Mengqian Zhang, Dong Yang

Mycopathologia. 2016 Jun;181(5-6):329-39.

PMID: 26700222

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