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DC260126

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For Research Use Only | Not For Clinical Use
CATAP346692044
CAS346692-04-4
Molecular Weight307.38
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

DC260126, a Small-Molecule Antagonist of GPR40, Improves Insulin Tolerance but Not Glucose Tolerance in Obese Zucker Rats

Xiaodong Zhang, Guirui Yan, Yiming Li, Weiliang Zhu, Heyao Wang

Biomed Pharmacother. 2010 Nov;64(9):647-51.

PMID: 20888730

1

DC260126: A Small-Molecule Antagonist of GPR40 That Protects Against Pancreatic β-Cells Dysfunction in db/db Mice

Peng Sun, Ting Wang, Yuren Zhou, Hong Liu, Hualiang Jiang, Weiliang Zhu, Heyao Wang

PLoS One. 2013 Jun 11;8(6):e66744.

PMID: 23776696

1

G Protein-Coupled Receptor 40 Activation Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice via the Upregulation of glucagon-likepeptide-2

Shinichi Kato, Daichi Utsumi, Kenjiro Matsumoto

J Pharmacol Sci. 2019 Jun;140(2):144-152.

PMID: 31242961

1

Inhibition of GPR40 Protects MIN6 β Cells From Palmitate-Induced ER Stress and Apoptosis

Jinwei Wu, Peng Sun, Xiaodong Zhang, Hong Liu, Hualiang Jiang, Weiliang Zhu, Heyao Wang

J Cell Biochem. 2012 Apr;113(4):1152-8.

PMID: 22275065

1

Quercetin-3-oleoyl Derivatives as New GPR40 Agonists: Molecular Docking Studies and Functional Evaluation

Gabriele Carullo, Mariarita Perri, Fabrizio Manetti, Francesca Aiello, Maria Cristina Caroleo, Erika Cione

Bioorg Med Chem Lett. 2019 Jul 15;29(14):1761-1764.

PMID: 31104992

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