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(−)-Deguelin

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For Research Use Only | Not For Clinical Use
CATAP522178
CAS522-17-8
Structure
MDL NumberMFCD01740600
Molecular Weight394.42
InChI KeyORDAZKGHSNRHTD-UXHICEINSA-N
Description>98% (HPLC), powder
SolubilityDMSO: 10 mg/mL, clear
Assay>98% (HPLC)
Colorwhite to beige
Formpowder
MP85-87 °C (lit.)
Size5MG
Storage Conditions−20°C
1

Biopharmacological Considerations for Accelerating Drug Development of Deguelin, a Rotenoid With Potent Chemotherapeutic and Chemopreventive Potential

Rahel Sarah Varughese, Walter Sze-Tung Lam, Ahmad Abdurrahman Bin Hanifah Marican, S Hema Viganeshwari, Anuja Satish Bhave, Nicholas L Syn, Jigang Wang, Andrea Li-Ann Wong, Alan Prem Kumar, Peter E Lobie, etc.

Cancer. 2019 Jun 1;125(11):1789-1798.

PMID: 30933320

1

Deguelin and Its Role in Chronic Diseases

Jonathan Boyd, Alice Han

Adv Exp Med Biol. 2016;929:363-375.

PMID: 27771933

1

Deguelin Induces Apoptosis in Colorectal Cancer Cells by Activating the p38 MAPK Pathway

Liubo Chen, Kai Jiang, Haiyan Chen, Yang Tang, Xinyi Zhou, Yinuo Tan, Ying Yuan, Qian Xiao, Kefeng Ding

Cancer Manag Res. 2018 Dec 20;11:95-105.

PMID: 30588113

1

Inhibition of Cancer Stem-Like Phenotype by Curcumin and Deguelin in CAL-62 Anaplastic Thyroid Cancer Cells

Mehmet A Kocdor, Hakan Cengiz, Halil Ates, Hilal Kocdor

Anticancer Agents Med Chem. 2019;19(15):1887-1898.

PMID: 31584382

1

The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication Within Fibroblasts

Masatoshi Nukui, Christine M O'Connor, Eain A Murphy

Viruses. 2018 Nov 7;10(11):614.

PMID: 30405048

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