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Diisopropyl-fluorophosphatase

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For Research Use Only | Not For Clinical Use
CATAP9032182
CAS9032-18-2
Description≥30 U/mg
Size10MG, 50MG
1

Binding of a Designed Substrate Analogue to Diisopropyl Fluorophosphatase: Implications for the Phosphotriesterase Mechanism

Marc-Michael Blum, Frank Löhr, Andre Richardt, Heinz Rüterjans, Julian C-H Chen

J Am Chem Soc. 2006 Oct 4;128(39):12750-7.

PMID: 17002369

1

In Vitro and in Vivo Efficacy of PEGylated Diisopropyl Fluorophosphatase (DFPase)

Marco Melzer, Anne Heidenreich, Frederic Dorandeu, Jürgen Gäb, Kai Kehe, Horst Thiermann, Thomas Letzel, Marc-Michael Blum

Drug Test Anal. Mar-Apr 2012;4(3-4):262-70.

PMID: 22174192

1

Reversed Enantioselectivity of Diisopropyl Fluorophosphatase Against Organophosphorus Nerve Agents by Rational Design

Marco Melzer, Julian C-H Chen, Anne Heidenreich, Jürgen Gäb, Marianne Koller, Kai Kehe, Marc-Michael Blum

J Am Chem Soc. 2009 Dec 2;131(47):17226-32.

PMID: 19894712

1

Theoretical Studies on Catalysis Mechanisms of Serum Paraoxonase 1 and Phosphotriesterase Diisopropyl Fluorophosphatase Suggest the Alteration of Substrate Preference From Paraoxonase to DFP

Hao Zhang, Ling Yang, Ying-Ying Ma, Chaoyuan Zhu, Shenghsien Lin, Rong-Zhen Liao

Molecules. 2018 Jul 7;23(7):1660.

PMID: 29986514

1

X-ray Structure of Perdeuterated Diisopropyl Fluorophosphatase (DFPase): Perdeuteration of Proteins for Neutron Diffraction

Marc Michael Blum, Stephen J Tomanicek, Harald John, B Leif Hanson, Heinz Rüterjans, Benno P Schoenborn, Paul Langan, Julian C H Chen

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Apr 1;66(Pt 4):379-85.

PMID: 20383004

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