Disperse Yellow 7

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For Research Use Only | Not For Clinical Use

CAT	APS6300374
CAS	6300-37-4
Structure
Synonyms	Celliton Yellow 5R, Serisol Fast Yellow N 5RD, Samaron Yellow 5RL, Phenol, 2-methyl-4-[[4-(phenylazo)phenyl]azo]- (9CI), Miketon Polyester Yellow 5R, Palanil Yellow 5R, Disperse Yellow 7, Kayalon Fast Yellow 4R, Kayalon Polyester Yellow 4R-E, Tersetile Yellow 5R, NSC 45573, Yohao Disperse Yellow 4RE, Tulasteron Fast Yellow 5R-B, Cilla Fast Yellow 5R, Azofenol 4K, Disperse Fast Yellow 4K, Supracet Fast Yellow 4R, Tersetile Yellow 5RL, C.I. 26090, Resolin Yellow 5R, Kayalon Polyester Yellow RF, Vonteryl Yellow 3R, Celliton Fast Yellow 5R, Dianix Yellow 5R-E, Palanil Yellow 5RX,Phenol, 2-methyl-4-[2-[4-(2-phenyldiazenyl)phenyl]diazenyl]-, Yellow Stable 4K, Disperse Yellow Stable 4K, Dianix Fast Yellow 5R, Acetate Fast Yellow 5RL, C.I. Disperse Yellow 7 (7CI,8CI), Celliton Discharge Yellow 5RL
IUPAC Name	2-methyl-4-[(E)-[4-[(E)-phenyldiazenyl]phenyl]diazenyl]phenol
Molecular Weight	316.36
Molecular Formula	C19H16N4O
Canonical SMILES	Cc1cc(ccc1O)N=Nc2ccc(cc2)N=Nc3ccccc3
InChI	InChI=1S/C19H16N4O/c1-14-13-18(11-12-19(14)24)23-22-17-9-7-16(8-10-17)21-20-15-5-3-2-4-6-15/h2-13,24H,1H3/b21-20+,23-22+

Accurate Mass	316.1324
Format	Neat
Shipping	Room Temperature
Storage Conditions	+20°C
Subcategory	Dyes and metabolites

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Case Study

Disperse Yellow 7 Induces Heat Shock Protein mRNA

Mathieu-Denoncourt, Justine, et al. Environmental science & technology 48.5 (2014): 2952-2961.

Targeted transcriptional analysis was employed to evaluate the effects of Disperse Yellow 7 (DY7) on cellular stress, thyroid hormone, and reproductive systems. In experiments with DY7-contaminated water, no changes in gene expression were detected. Similarly, animals exposed to sediments containing DY7 did not exhibit changes in mRNA levels of trbeta, dio2, hsp30, and eralpha at any tested concentration. However, after exposure to the highest treatment concentration, hsp70 and hsp90 mRNA levels increased by 2.5-fold and 2.4-fold respectively (p < 0.01). Additionally, a significant 1.8-fold increase in hsp90 mRNA levels was observed at a treatment concentration of 2 µg/g (p = 0.016). Exposure to DY7 also impacted androgen-related genes ar and srd5α2. The expression of ar mRNA was reduced by approximately 2-fold in treated groups, but this reduction was statistically significant only in the 14 and 209 µg/g treatments (p = 0.029). Moreover, at the highest DY7 concentration (209 µg/g), srd5α2 mRNA was induced 2.6-fold (p = 0.024).

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