DNMT3A/DNMT3L active human - Analytical Products / Alfa Chemistry

CAT

IAR42413459

Description	recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE)
Assay	≥90% (SDS-PAGE)
Form	aqueous solution; 52 kDa (DNMT3L); NM_175629 (DNMT3A)
Size	10μG
Storage Conditions	−70°C

1

Structural Basis for DNMT3A-mediated De Novo DNA Methylation

Zhi-Min Zhang, Rui Lu, Pengcheng Wang, Yang Yu, Dongliang Chen, Linfeng Gao, Shuo Liu, Debin Ji, Scott B Rothbart, Yinsheng Wang, Gang Greg Wang, Jikui Song

Nature. 2018 Feb 15;554(7692):387-391.

PMID: 29414941

1

Structural Insight Into Autoinhibition and Histone H3-induced Activation of DNMT3A

Xue Guo, Ling Wang, Jie Li, Zhanyu Ding, Jianxiong Xiao, Xiaotong Yin, Shuang He, Pan Shi, Liping Dong, Guohong Li, Changlin Tian, Jiawei Wang, Yao Cong, Yanhui Xu

Nature. 2015 Jan 29;517(7536):640-4.

PMID: 25383530

1

Structure of Dnmt3a Bound to Dnmt3L Suggests a Model for De Novo DNA Methylation

Da Jia, Renata Z Jurkowska, Xing Zhang, Albert Jeltsch, Xiaodong Cheng

Nature. 2007 Sep 13;449(7159):248-51.

PMID: 17713477

1

Targeted Methylation and Gene Silencing of VEGF-A in Human Cells by Using a Designed Dnmt3a-Dnmt3L Single-Chain Fusion Protein With Increased DNA Methylation Activity

Abu Nasar Siddique, Suneetha Nunna, Arumugam Rajavelu, Yingying Zhang, Renata Z Jurkowska, Richard Reinhardt, Marianne G Rots, Sergey Ragozin, Tomasz P Jurkowski, Albert Jeltsch

J Mol Biol. 2013 Feb 8;425(3):479-91.

PMID: 23220192

1

The R882H Substitution in the Human

Jonathan E Sandoval, Norbert O Reich

J Biol Chem. 2019 Nov 29;294(48):18207-18219.

PMID: 31640986

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