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DOV 216,303

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For Research Use Only | Not For Clinical Use
CATAP86215363
CAS86215-36-3
Structure
MDL NumberMFCD06407666
Molecular Weight264.58
InChI KeyKAGBHVBIOJBGBD-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥10 mg/mL
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions−20°C
1

Addiction-related Effects of DOV 216,303 and Cocaine: A Comparative Study in the Mouse

Gunnar Sørensen, Henriette Husum, Lise T Brennum, Christoffer Bundgaard, Liliana C P Montezinho, Arne Mørk, Gitta Wörtwein, David P D Woldbye

Basic Clin Pharmacol Toxicol. 2014 Jun;114(6):451-9.

PMID: 24314270

1

The Potential and Limitations of DOV 216,303 as a Triple Reuptake Inhibitor for the Treatment of Major Depression: A Microdialysis Study in Olfactory Bulbectomized Rats

J Prins, K G C Westphal, G A H Korte-Bouws, M S Quinton, R Schreiber, B Olivier, S M Korte

Pharmacol Biochem Behav. 2011 Jan;97(3):444-52.

PMID: 20934452

1

The Triple Monoamine Re-Uptake Inhibitor DOV 216,303 Promotes Functional Recovery After Spinal Cord Contusion Injury in Mice

Tak-Ho Chu, Karen Cummins, Peter K Stys

Neurosci Lett. 2018 May 14;675:1-6.

PMID: 29578004

1

The Triple Monoaminergic Reuptake Inhibitor DOV 216,303 Has Antidepressant Effects in the Rat Olfactory Bulbectomy Model and Lacks Sexual Side Effects

M E Breuer, J S W Chan, R S Oosting, L Groenink, S M Korte, U Campbell, R Schreiber, T Hanania, E M S Snoeren, M Waldinger, B Olivier

Eur Neuropsychopharmacol. 2008 Dec;18(12):908-16.

PMID: 18789657

1

The Triple Reuptake Inhibitor DOV 216,303 Induces Long-Lasting Enhancement of Brain Reward Activity as Measured by Intracranial Self-Stimulation in Rats

Jolanda Prins, Paul J Kenny, Ivo Doomernik, Rudy Schreiber, Berend Olivier, S Mechiel Korte

Eur J Pharmacol. 2012 Oct 15;693(1-3):51-6.

PMID: 23010469

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