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(E/Z)-BCI hydrochloride

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For Research Use Only | Not For Clinical Use
CATAP95130237
CAS95130-23-7
MDL NumberMFCD16875416
Molecular Weight353.89
InChI KeyJPATUDRDKCLPTI-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

DUSP6 Inhibitor (E/Z)-BCI Hydrochloride Attenuates Lipopolysaccharide-Induced Inflammatory Responses in Murine Macrophage Cells via Activating the Nrf2 Signaling Axis and Inhibiting the NF-κB Pathway

Fan Zhang, Bufu Tang, Zijiao Zhang, Di Xu, Guowu Ma

Inflammation. 2019 Apr;42(2):672-681.

PMID: 30506106

1

Inhibition of DUSP6 Sensitizes Ovarian Cancer Cells to Chemotherapeutic Agents via Regulation of ERK Signaling Response Genes

Nicole E James, Lindsey Beffa, Matthew T Oliver, Ashley D Borgstadt, Jenna B Emerson, Clinton O Chichester, Naohiro Yano, Richard N Freiman, Paul A DiSilvestro, Jennifer R Ribeiro

Oncotarget. 2019 May 21;10(36):3315-3327.

PMID: 31164954

1

Pharmacological Inhibition of DUSP6 Suppresses Gastric Cancer Growth and Metastasis and Overcomes Cisplatin Resistance

Qi-Nian Wu, Yi-Fu Liao, Yun-Xin Lu, Yun Wang, Jia-Huan Lu, Zhao-Lei Zeng, Qi-Tao Huang, Hui Sheng, Jing-Ping Yun, Dan Xie, Huai-Qiang Ju, Rui-Hua Xu

Cancer Lett. 2018 Jan 1;412:243-255.

PMID: 29050982

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