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E3330

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For Research Use Only | Not For Clinical Use
CATAP136164664
CAS136164-66-4
MDL NumberMFCD00901331
Molecular Weight378.46
InChI KeyAALSSIXXBDPENJ-FYWRMAATSA-N
Description≥98% (HPLC)
SolubilityDMSO: >20 mg/mL
Assay≥98% (HPLC)
Colorred to orange
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Apurinic/Apyrimidinic Endonuclease 1/Redox Factor-1 (Ape1/Ref-1) Modulates Antigen Presenting Cell-mediated T Helper Cell Type 1 Responses

Nasrin Akhter, Yuji Takeda, Hidetoshi Nara, Akemi Araki, Naoto Ishii, Naoki Asao, Hironobu Asao

J Biol Chem. 2016 Nov 4;291(45):23672-23680.

PMID: 27637330

1

Inhibition of APE1/Ref-1 Redox Activity Rescues Human Retinal Pigment Epithelial Cells From Oxidative Stress and Reduces Choroidal Neovascularization

Y Li, X Liu, T Zhou, M R Kelley, P Edwards, H Gao, X Qiao

Redox Biol. 2014 Feb 21;2:485-94.

PMID: 24624338

1

Inhibition of apurinic/apyrimidinic Endonuclease I's Redox Activity Revisited

Jun Zhang, Meihua Luo, Daniela Marasco, Derek Logsdon, Kaice A LaFavers, Qiujia Chen, April Reed, Mark R Kelley, Michael L Gross, Millie M Georgiadis

Biochemistry. 2013 Apr 30;52(17):2955-66.

PMID: 23597102

1

NMR Studies Reveal an Unexpected Binding Site for a Redox Inhibitor of AP Endonuclease 1

Brittney A Manvilla, Orrette Wauchope, Katherine L Seley-Radtke, Alexander C Drohat

Biochemistry. 2011 Dec 6;50(48):10540-9.

PMID: 22032234

1

Suppression of Choroidal Neovascularization Through Inhibition of APE1/Ref-1 Redox Activity

Yue Li, Xiuli Liu, Tongrong Zhou, Mark R Kelley, Paul A Edwards, Hua Gao, Xiaoxi Qiao

Invest Ophthalmol Vis Sci. 2014 Jun 26;55(7):4461-9.

PMID: 24970265

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