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EB1089

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For Research Use Only | Not For Clinical Use
CATAP134404527
CAS134404-52-7
Structure
MDL NumberMFCD00871599
Molecular Weight454.68
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size1MG, 5MG
Storage Conditions−20°C
1

Apoptosis Is Induced by the Active Metabolite of Vitamin D3 and Its Analogue EB1089 in Colorectal Adenoma and Carcinoma Cells: Possible Implications for Prevention and Therapy

G D Díaz, C Paraskeva, M G Thomas, L Binderup, A Hague

Cancer Res. 2000 Apr 15;60(8):2304-12.

PMID: 10786699

1

Calcitriol Inhibits the Proliferation of Triple-Negative Breast Cancer Cells Through a Mechanism Involving the Proinflammatory Cytokines IL-1

Isela Martínez-Reza, Lorenza Díaz, David Barrera, Mariana Segovia-Mendoza, Sigifredo Pedraza-Sánchez, Giovanny Soca-Chafre, Fernando Larrea, Rocío García-Becerra

J Immunol Res. 2019 Apr 10;2019:6384278.

PMID: 31093512

1

Vitamin D Analog EB1089 Inhibits Aromatase Expression by Dissociation of Comodulator WSTF From the CYP19A1 Promoter-A New Regulatory Pathway for Aromatase

Johan Lundqvist, Susanne Kofoed Hansen, Anne E Lykkesfeldt

Biochim Biophys Acta. 2013 Jan;1833(1):40-7.

PMID: 23085504

1

Vitamin D Analogues: Potential Use in Cancer Treatment

Michael J Duffy, Alyson Murray, Naoise C Synnott, Norma O'Donovan, John Crown

Crit Rev Oncol Hematol. 2017 Apr;112:190-197.

PMID: 28325259

1

Vitamin D Pathway Activation Selectively Deactivates Signal Transducer and Activator of Transcription (STAT) Proteins and Inflammatory Cytokine Production in Natural Killer Leukemic Large Granular Lymphocytes

Kristine C Olson, Paige M Kulling Larkin, Rossana Signorelli, Cait E Hamele, Thomas L Olson, Mark R Conaway, David J Feith, Thomas P Loughran Jr

Cytokine. 2018 Nov;111:551-562.

PMID: 30455079

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