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Efavirenz

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For Research Use Only | Not For Clinical Use
CATAP154598524
CAS154598-52-4
Structure
MDL NumberMFCD05662344
Molecular Weight315.67
InChI KeyXPOQHMRABVBWPR-ZDUSSCGKSA-N
1

Adverse Neuropsychiatric Events and Recreational Use of Efavirenz and Other HIV-1 Antiretroviral Drugs

Dhwanil A Dalwadi, Luis Ozuna, Brian H Harvey, Michelle Viljoen, John A Schetz

Pharmacol Rev. 2018 Jul;70(3):684-711.

PMID: 29945900

1

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2B6 and Efavirenz-Containing Antiretroviral Therapy

Zeruesenay Desta, Roseann S Gammal, Li Gong, Michelle Whirl-Carrillo, Aditya H Gaur, Chonlaphat Sukasem, Jennifer Hockings, Alan Myers, Marelize Swart, Rachel F Tyndale, Collen Masimirembwa, Otito F Iwuchukwu, etc.

Clin Pharmacol Ther. 2019 Oct;106(4):726-733.

PMID: 31006110

1

CYP46A1 Activation by Efavirenz Leads to Behavioral Improvement Without Significant Changes in Amyloid Plaque Load in the Brain of 5XFAD Mice

Alexey M Petrov, Morrie Lam, Natalia Mast, Jean Moon, Yong Li, Erin Maxfield, Irina A Pikuleva

Neurotherapeutics. 2019 Jul;16(3):710-724.

PMID: 31062296

1

Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry

Pan-Fen Wang, Alicia Neiner, Evan D Kharasch

Drug Metab Dispos. 2019 Oct;47(10):1195-1205.

PMID: 31324697

1

Efavirenz Reduces Renal Excretion of Lamivudine in Rats by Inhibiting Organic Cation Transporters (OCT, Oct) and Multidrug and Toxin Extrusion Proteins (MATE, Mate)

Martina Ceckova, Josef Reznicek, Birgit Deutsch, Martin F Fromm, Frantisek Staud

PLoS One. 2018 Aug 16;13(8):e0202706.

PMID: 30114293

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