EGFR (L858R) Active human - Analytical Products / Alfa Chemistry

CAT

IAR42413242

Description	recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE)
Assay	≥70% (SDS-PAGE)
Form	aqueous solution
Size	10μG
Storage Conditions	−70°C

1

Chemotherapy Drug Response to the L858R-induced Conformational Change of EGFR Activation Loop in Lung Cancer

Xi Ding, Xingcai Liu, Xiaoyun Song, Jun Yao

Mol Inform. 2016 Oct;35(10):529-537.

PMID: 27643705

1

Dacomitinib, a Second-Generation Irreversible Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor (EGFR-TKI) to Treat Non-Small Cell Lung Cancer

T Nagano, M Tachihara, Y Nishimura

Drugs Today (Barc). 2019 Apr;55(4):231-236.

PMID: 31050691

1

In-silico Evidences for Binding of Glucokinase Activators to EGFR C797S to Overcome EGFR Resistance Obstacle With Mutant-Selective Allosteric Inhibition

Harun Patel, Rahul Pawara, Sanjay Surana

Comput Biol Chem. 2018 Jun;74:167-189.

PMID: 29627693

1

Withanolide A Extends the Lifespan in Human EGFR-driven Cancerous Caenorhabditis Elegans

Bashir Akhlaq Akhoon, Laxmi Rathor, Rakesh Pandey

Exp Gerontol. 2018 Apr;104:113-117.

PMID: 29427754

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