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EGFR (T790M L858R) Active human

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For Research Use Only | Not For Clinical Use
CATIAR42413243
Descriptionrecombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE)
Assay≥70% (SDS-PAGE)
Formaqueous solution
Size10μG
Storage Conditions−70°C
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Osimertinib

Umberto Malapelle, Biagio Ricciuti, Sara Baglivo, Francesco Pepe, Pasquale Pisapia, Paola Anastasi, Marco Tazza, Angelo Sidoni, Anna M Liberati, Guido Bellezza, Rita Chiari, Giulio Metro

Recent Results Cancer Res. 2018;211:257-276.

PMID: 30069773

1

Overcoming EGFR(T790M) and EGFR(C797S) Resistance With Mutant-Selective Allosteric Inhibitors

Yong Jia, Cai-Hong Yun, Eunyoung Park, Dalia Ercan, Mari Manuia, Jose Juarez, Chunxiao Xu, Kevin Rhee, Ting Chen, Haikuo Zhang, Sangeetha Palakurthi, Jaebong Jang, Gerald Lelais, Michael DiDonato, Badry Bursulaya, etc.

Nature. 2016 Jun 2;534(7605):129-32.

PMID: 27251290

1

Role of Osimertinib in the Treatment of EGFR-mutation Positive Non-Small-Cell Lung Cancer

Jennifer W Carlisle, Suresh S Ramalingam

Future Oncol. 2019 Mar;15(8):805-816.

PMID: 30657347

1

Small Molecule Inhibitors Targeting the EGFR/ErbB Family of Protein-Tyrosine Kinases in Human Cancers

Robert Roskoski Jr

Pharmacol Res. 2019 Jan;139:395-411.

PMID: 30500458

1

Targeting EGFR

Xiaoyun Lu, Lei Yu, Zhang Zhang, Xiaomei Ren, Jeff B Smaill, Ke Ding

Med Res Rev. 2018 Sep;38(5):1550-1581.

PMID: 29377179

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