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EHop-016

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For Research Use Only | Not For Clinical Use
CATAP1380432325
CAS1380432-32-5
MDL NumberMFCD23143628
Molecular Weight430.55
InChI KeyAFTZZRFCMOAFCR-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Characterization of EHop-016, Novel Small Molecule Inhibitor of Rac GTPase

Brenda L Montalvo-Ortiz, Linette Castillo-Pichardo, Eliud Hernández, Tessa Humphries-Bickley, Alina De la Mota-Peynado, Luis A Cubano, Cornelis P Vlaar, Suranganie Dharmawardhane

J Biol Chem. 2012 Apr 13;287(16):13228-38.

PMID: 22383527

1

Development of EHop-016: A Small Molecule Inhibitor of Rac

Suranganie Dharmawardhane, Eliud Hernandez, Cornelis Vlaar

Enzymes. 2013;33 Pt A(Pt A):117-46.

PMID: 25033803

1

Long Noncoding RNA LCAT1 Functions as a ceRNA to Regulate RAC1 Function by Sponging miR-4715-5p in Lung Cancer

Juze Yang, Qiongzi Qiu, Xinyi Qian, Jiani Yi, Yiling Jiao, Mengqian Yu, Xufan Li, Jia Li, Chunyi Mi, Jisong Zhang, Bingjian Lu, Enguo Chen, Pengyuan Liu, Yan Lu

Mol Cancer. 2019 Nov 29;18(1):171.

PMID: 31779616

1

Pharmacokinetics of Rac Inhibitor EHop-016 in Mice by Ultra-Performance Liquid Chromatography Tandem Mass Spectrometry

Tessa Humphries-Bickley, Linette Castillo-Pichardo, Francheska Corujo-Carro, Jorge Duconge, Eliud Hernandez-O'Farrill, Cornelis Vlaar, Jose F Rodriguez-Orengo, Luis Cubano, Suranganie Dharmawardhane

J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Feb 15;981-982:19-26.

PMID: 25594952

1

The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model

Linette Castillo-Pichardo, Tessa Humphries-Bickley, Columba De La Parra, Ingrid Forestier-Roman, Magaly Martinez-Ferrer, Eliud Hernandez, Cornelis Vlaar, Yancy Ferrer-Acosta, Anthony V Washington, Luis A Cubano, etc.

Transl Oncol. 2014 Oct 24;7(5):546-55.

PMID: 25389450

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