Eltrombopag Impurity 9 (Hydrochloride)

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For Research Use Only | Not For Clinical Use

CAT	APB05636
Synonyms	3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid hydrochloride
Molecular Weight	265.53
Molecular Formula	C13H11NO3·HCl

What is another name for Eltrombopag Impurity 9 (Hydrochloride)?

Synonym: 3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid hydrochloride

What is the molecular weight of Eltrombopag Impurity 9 (Hydrochloride)?

Molecular Weight: 265.53

What is the molecular formula of Eltrombopag Impurity 9 (Hydrochloride)?

Molecular Formula: C13H11NO3·HCl

What is the chemical structure of Eltrombopag Impurity 9 (Hydrochloride)?

The chemical structure is [1,1'-biphenyl]-3-carboxylic acid with an amino and hydroxyl group at the 2' and 3' positions, respectively, and a hydrochloride salt.

How is Eltrombopag Impurity 9 (Hydrochloride) typically used?

It is used as a reference standard or impurity in the testing and analysis of Eltrombopag drug products.

What is the significance of identifying and quantifying Eltrombopag Impurity 9 (Hydrochloride) in pharmaceutical formulations?

It ensures the quality, safety, and efficacy of the drug product.

How is Eltrombopag Impurity 9 (Hydrochloride) synthesized and isolated in laboratory settings?

It is synthesized by various chemical reactions and isolated through purification techniques such as chromatography.

What are the possible methods for detecting and quantifying Eltrombopag Impurity 9 (Hydrochloride)?

Methods like high-performance liquid chromatography (HPLC) and mass spectrometry (MS) can be utilized.

How stable is Eltrombopag Impurity 9 (Hydrochloride) under normal storage conditions?

It is recommended to store the compound in a cool, dry place and protect it from light to maintain stability.

What are the potential risks associated with the presence of Eltrombopag Impurity 9 (Hydrochloride) in drug formulations?

Impurities can affect the purity, stability, and efficacy of the drug product, leading to potential adverse effects on patients.

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