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EMD386088

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For Research Use Only | Not For Clinical Use
CATAP1171123468
CAS1171123-46-8
MDL NumberMFCD09038557
Molecular Weight283.20
InChI KeyWWSNDUWIZDYGIQ-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥16 mg/mL
Assay≥98% (HPLC)
Coloryellow
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

5-HT6 Receptor Agonist EMD386088 Impairs Behavioral Flexibility and Working Memory

Dionisio A Amodeo, Sophie Peterson, Alma Pahua, Rebekah Posadas, Armando Hernandez, Emily Hefner, David Qi, Jesus Vega

Behav Brain Res. 2018 Sep 3;349:8-15.

PMID: 29715539

1

5-HT6 Receptor Ligands, EMD386088 and SB258585, Differentially Regulate 5-HT6 Receptor-Independent Events

Hyung-Mun Yun, Hyewhon Rhim

Toxicol In Vitro. 2011 Dec;25(8):2035-40.

PMID: 21864673

1

Chronic Antidepressant-Like Effect of EMD386088, a Partial 5-HT

Magdalena Jastrzębska-Więsek, Joanna Gdula-Argasińska, Agata Siwek, Anna Partyka, Bernadeta Szewczyk, Marcin Kołaczkowski, Anna Wesołowska

Pharmacol Rep. 2018 Dec;70(6):1047-1056.

PMID: 30292720

1

Study of a Mechanism Responsible for Potential Antidepressant Activity of EMD 386088, a 5-HT6 Partial Agonist in Rats

Magdalena Jastrzębska-Więsek, Agata Siwek, Anna Partyka, Lucyna Antkiewicz-Michaluk, Jerzy Michaluk, Irena Romańska, Marcin Kołaczkowski, Anna Wesołowska

Naunyn Schmiedebergs Arch Pharmacol. 2016 Aug;389(8):839-49.

PMID: 27106213

1

Study on the effect of EMD386088, a 5-HT 6 receptor partial agonist, in enhancing the anti-immobility action of some antidepressants in rats

Magdalena Jastrzębska-Więsek, Agata Siwek, Anna Partyka, Marcin Kołaczkowski, Maria Walczak, Magdalena Smolik, Gniewomir Latacz, Katarzyna Kieć-Kononowicz, Anna Wesołowska

Naunyn Schmiedebergs Arch Pharmacol. 2018 Jan;391(1):37-49.

PMID: 29079874

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