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(−)-Epothilone A

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For Research Use Only | Not For Clinical Use
CATAP152044536
CAS152044-53-6
Structure
MDL NumberMFCD26960884
Molecular Weight493.66
InChI KeyHESCAJZNRMSMJG-KKQRBIROSA-N
Descriptionfrom Sorangium cellulosum, >95% (HPLC), solid
Assay>95% (HPLC)
Formsolid; protect from light
Size10UG
Storage Conditions−20°C
1

Enzymatic Synthesis of Epothilone A Glycosides

Prakash Parajuli, Ramesh Prasad Pandey, Niranjan Koirala, Yeo Joon Yoon, Byung-Gee Kim, Jae Kyung Sohng

AMB Express. 2014 Mar 20;4:31.

PMID: 24949266

1

Gene Expression Profiling of Epothilone A-resistant Cells

Peter Atadja, Yan Yan-Neale, Harry Towbin, Frank Buxton, Dalia Cohen

Novartis Found Symp. 2002;243:119-32; discussion 132-6, 180-5.

PMID: 11990772

1

Metformin and Epothilone A Treatment Up Regulate Pro-Apoptotic PARP-1, Casp-3 and H2AX Genes and Decrease of AKT Kinase Level to Control Cell Death of Human Hepatocellular Carcinoma and Ovary Adenocarcinoma Cells

Aneta Rogalska, Barbara Bukowska, Agnieszka Marczak

Toxicol In Vitro. 2018 Mar;47:48-62.

PMID: 29117515

1

Microbial Transformation of Epothilone A by Aspergillus Niger AS 3.739

Yan-Liang Wang, He Wang, Yu-Xin Lu, Xiao-Chen Cheng, Li-Li Han, Shou-Jun Yuan, De-Xuan Yang, Qing-Lin Zhang, Chu-Tse Wu

J Asian Nat Prod Res. 2009;11(4):357-64.

PMID: 19431017

1

Suppression of Autophagy Enhances Preferential Toxicity of Epothilone A and Epothilone B in Ovarian Cancer Cells

Aneta Rogalska, Arkadiusz Gajek, Agnieszka Marczak

Phytomedicine. 2019 Aug;61:152847.

PMID: 31029905

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