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EUK-134

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For Research Use Only | Not For Clinical Use
CATAP81065761
CAS81065-76-1
Structure
Molecular Weight416.74
Description≥95% (HPLC)
SolubilityH2O: 2 mg/mL, clear (warmed)
Assay≥95% (HPLC)
Color, faint to very dark brown
Formpowder
Size10MG, 50MG
Storage Conditions−20°C
1

A Synthetic Superoxide dismutase/catalase Mimetic (EUK-134) Inhibits Membrane-Damage-Induced Activation of Mitogen-Activated Protein Kinase Pathways and Reduces p53 Accumulation in Ultraviolet B-exposed Primary Human Keratinocytes

David Decraene, Katrien Smaers, David Gan, Tom Mammone, Mary Matsui, Daniel Maes, Lieve Declercq, Marjan Garmyn

J Invest Dermatol. 2004 Feb;122(2):484-91.

PMID: 15009734

1

EUK-134 Ameliorates nNOSμ Translocation and Skeletal Muscle Fiber Atrophy During Short-Term Mechanical Unloading

John M Lawler, Mary Kunst, Jeff M Hord, Yang Lee, Kumar Joshi, Rachel E Botchlett, Angelo Ramirez, Daniel A Martinez

Am J Physiol Regul Integr Comp Physiol. 2014 Apr 1;306(7):R470-82.

PMID: 24477538

1

Mitoprotective Antioxidant EUK-134 Stimulates Fatty Acid Oxidation and Prevents Hypertrophy in H9C2 Cells

Sreeja Purushothaman, R Renuka Nair

Mol Cell Biochem. 2016 Sep;420(1-2):185-94.

PMID: 27514538

1

Superoxide dismutase/catalase Mimetic EUK-134 Prevents Diaphragm Muscle Weakness in Monocrotalin-Induced Pulmonary Hypertension

Koichi Himori, Masami Abe, Daisuke Tatebayashi, Jaesik Lee, Håkan Westerblad, Johanna T Lanner, Takashi Yamada

PLoS One. 2017 Feb 2;12(2):e0169146.

PMID: 28152009

1

The Manganese-Salen Compound EUK-134 and N-acetyl Cysteine Rescue From Zinc- And Paraquat-Induced Toxicity in Rat Polymorphonuclear Leukocytes

Ashutosh Kumar, Smriti Shukla, Amit Kumar Chauhan, Deepali Singh, Haushila Prasad Pandey, Chetna Singh

Chem Biol Interact. 2015 Apr 25;231:18-26.

PMID: 25724285

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