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EUK-8

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For Research Use Only | Not For Clinical Use
CATAP53177121
CAS53177-12-1
Molecular Weight356.69
Description≥95% (HPLC)
SolubilityH2O: 1 mg/mL, clear
Assay≥95% (HPLC)
Color, faint to very dark brown
Formpowder
Size10MG, 50MG
Storage Conditions−20°C
1

Antioxidant, EUK-8, Prevents Murine Dilated Cardiomyopathy

Satoru Kawakami, Akina Matsuda, Tadahiro Sunagawa, Yoshihiro Noda, Takao Kaneko, Shoichi Tahara, Yoshimi Hiraumi, Souichi Adachi, Hiromitsu Matsui, Katsuyuki Ando, Toshiro Fujita, Naoki Maruyama, Takuji Shirasawa, etc.

Circ J. 2009 Nov;73(11):2125-34.

PMID: 19749480

1

EUK-8 a Synthetic Catalytic Scavenger of Reactive Oxygen Species Protects Isolated Iron-Overloaded Rat Heart From Functional and Structural Damage Induced by ischemia/reperfusion

S Pucheu, F Boucher, T Sulpice, N Tresallet, Y Bonhomme, B Malfroy, J de Leiris

Cardiovasc Drugs Ther. 1996 Jul;10(3):331-9.

PMID: 8877076

1

EUK-8, a Superoxide Dismutase and Catalase Mimetic, Reduces Cardiac Oxidative Stress and Ameliorates Pressure Overload-Induced Heart Failure in the Harlequin Mouse Mutant

Vanessa P M van Empel, Anne T Bertrand, Ralph J van Oort, Roel van der Nagel, Markus Engelen, Harold V van Rijen, Pieter A Doevendans, Harry J Crijns, Susan L Ackerman, Wim Sluiter, Leon J De Windt

J Am Coll Cardiol. 2006 Aug 15;48(4):824-32.

PMID: 16904556

1

EUK-8, a Synthetic Superoxide Dismutase and Catalase Mimetic, Ameliorates Acute Lung Injury in Endotoxemic Swine

P K Gonzalez, J Zhuang, S R Doctrow, B Malfroy, P F Benson, M J Menconi, M P Fink

J Pharmacol Exp Ther. 1995 Nov;275(2):798-806.

PMID: 7473169

1

Role of Mitochondria and Mitochondria-Targeted Agents in Non-Alcoholic Fatty Liver Disease

Thekkuttuparambil Ananthanarayanan Ajith

Clin Exp Pharmacol Physiol. 2018 May;45(5):413-421.

PMID: 29112771

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