EZH2 / EED / SUZ12 human - Analytical Products / Alfa Chemistry

CAT

IAR42416074

Description	recombinant, expressed in baculovirus infected insect cells, ≥90% (SDS-PAGE)
Assay	≥90% (SDS-PAGE)
Form	aqueous solution; 86 kDa (EZH2); 87 kDa (SUZ12); NM_004456 (EZH2); NM_015355 (SUZ12)
Size	50μG
Storage Conditions	−70°C

1

An Allosteric PRC2 Inhibitor Targeting the H3K27me3 Binding Pocket of EED

Wei Qi, Kehao Zhao, Justin Gu, Ying Huang, Youzhen Wang, Hailong Zhang, Man Zhang, Jeff Zhang, Zhengtian Yu, Ling Li, Lin Teng, Shannon Chuai, Chao Zhang, Mengxi Zhao, HoMan Chan, Zijun Chen, Douglas Fang, etc.

Nat Chem Biol. 2017 Apr;13(4):381-388.

PMID: 28135235

1

Expression and Clinicopathological Significance of EED, SUZ12 and EZH2 mRNA in Colorectal Cancer

Yan-Long Liu, Xu Gao, Yang Jiang, Gan Zhang, Zi-Cheng Sun, Bin-Bin Cui, Yan-Mei Yang

J Cancer Res Clin Oncol. 2015 Apr;141(4):661-9.

PMID: 25326896

1

microRNA-124a Suppresses PHF19 Over-Expression, EZH2 Hyper-Activation, and Aberrant Cell Proliferation in Human Glioma

Jian Lu, Hongming Ji, Huoquan Tang, Zhongye Xu

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1610-1617.

PMID: 30131250

1

Polycomb Group Protein Expression During Differentiation of Human Embryonic Stem Cells Into Pancreatic Lineage in Vitro

Prasad Pethe, Punam Nagvenkar, Deepa Bhartiya

BMC Cell Biol. 2014 May 24;15:18.

PMID: 24885493

1

The JAZF1-SUZ12 Fusion Protein Disrupts PRC2 Complexes and Impairs Chromatin Repression During Human Endometrial Stromal Tumorogenesis

Xianyong Ma, Jinglan Wang, Jianhui Wang, Charles X Ma, Xiaobin Gao, Vytas Patriub, Jeffrey L Sklar

Oncotarget. 2017 Jan 17;8(3):4062-4078.

PMID: 27845897

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