FAK Inhibitor 14

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For Research Use Only | Not For Clinical Use

CAT	AP4506665-A
CAS	4506-66-5
Molecular Weight	284.01
EC Number	224-822-6

Description	≥95% (HPLC)
Solubility	H2O: 20 mg/mL, clear
Assay	≥95% (HPLC)
Color	, faint purple to dark brown
Form	powder
Size	10MG, 50MG
Storage Conditions	room temp

FAK-Copy-Gain Is a Predictive Marker for Sensitivity to FAK Inhibition in Breast Cancer

Young-Ho Kim, Hyun-Kyoung Kim, Hee Yeon Kim, HyeRan Gawk, Seung-Hyun Bae, Hye Won Sim, Eun-Kyung Kang, Ju-Young Seoh, Hyonchol Jang, Kyeong-Man Hong

Cancers (Basel). 2019 Sep 2;11(9):1288.

PMID: 31480645

miR-125a-5p Regulation Increases Phosphorylation of FAK That Contributes to Imatinib Resistance in Gastrointestinal Stromal Tumors

Wen-Kuan Huang, Pinar Akçakaya, Anastasia Gangaev, Linkiat Lee, Katarina Zeljic, Praveensingh Hajeri, Erik Berglund, Mehran Ghaderi, Jan Åhlén, Robert Bränström, Catharina Larsson, Weng-Onn Lui

Exp Cell Res. 2018 Oct 1;371(1):287-296.

PMID: 30149002

Osteopontin-Enhanced Autophagy Attenuates Early Brain Injury via FAK-ERK Pathway and Improves Long-Term Outcome After Subarachnoid Hemorrhage in Rats

Chengmei Sun, Budbazar Enkhjargal, Cesar Reis, Tongyu Zhang, Qiquan Zhu, Keren Zhou, Zhiyi Xie, Lingyun Wu, Jiping Tang, Xiaodan Jiang, John H Zhang

Cells. 2019 Aug 27;8(9):980.

PMID: 31461955

Repulsive Guidance Molecule a Suppresses Seizures and Mossy Fiber Sprouting via the FAK‑p120RasGAP‑Ras Signaling Pathway

Mingyu Song, Fafa Tian, Huang Xia, Yuanyuan Xie

Mol Med Rep. 2019 Apr;19(4):3255-3262.

PMID: 30816469

The Role of FAK in the Secretion of MMP9 After CD147 Stimulation in Macrophages

Chen Yu, Yang Lixia, Guo Ruiwei, Shi Yankun, Ye Jinshan

Int Heart J. 2018 Mar 30;59(2):394-398.

PMID: 29563383

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