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Febuxostat Impurity 8

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For Research Use Only | Not For Clinical Use
CATAPB161797995
CAS161797-99-5
Structure
Synonymsethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Molecular Weight263.06
Molecular FormulaC13H13NO3S

What is the chemical name for Febuxostat Impurity 8?

The chemical name for Febuxostat Impurity 8 is ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate.

What is the CAS number for Febuxostat Impurity 8?

The CAS number for Febuxostat Impurity 8 is 161797-99-5.

What is the molecular weight of Febuxostat Impurity 8?

The molecular weight of Febuxostat Impurity 8 is 263.06.

What is the molecular formula of Febuxostat Impurity 8?

The molecular formula of Febuxostat Impurity 8 is C13H13NO3S.

How many carbon atoms are present in the molecular formula of Febuxostat Impurity 8?

There are 13 carbon atoms present in the molecular formula of Febuxostat Impurity 8.

What functional groups are present in the chemical structure of Febuxostat Impurity 8?

The chemical structure of Febuxostat Impurity 8 contains a phenyl group, a thiazole group, and an ester group.

What is the significance of Febuxostat Impurity 8 in pharmaceutical manufacturing?

Febuxostat Impurity 8 is an impurity that may affect the quality and purity of the final pharmaceutical product. Its presence needs to be monitored and controlled during manufacturing.

How is Febuxostat Impurity 8 detected and quantified in pharmaceutical formulations?

Febuxostat Impurity 8 can be detected and quantified using analytical techniques such as HPLC (High Performance Liquid Chromatography) or GC-MS (Gas Chromatography-Mass Spectrometry).

What are some potential methods for the synthesis of Febuxostat Impurity 8?

Febuxostat Impurity 8 can be synthesized through the esterification of 4-hydroxyphenylacetic acid with methyl 2-aminothiazole-5-carboxylate followed by hydrolysis.

How can the presence of Febuxostat Impurity 8 impact the efficacy and safety of the final pharmaceutical product?

The presence of Febuxostat Impurity 8 may alter the pharmacological properties of the final pharmaceutical product, potentially leading to reduced efficacy or unwanted side effects. therefore, controlling the levels of this impurity is crucial in maintaining the quality of the medication.

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