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Fenobam

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For Research Use Only | Not For Clinical Use
CATAP57653266
CAS57653-26-6
Structure
MDL NumberMFCD00868019
Molecular Weight266.68
InChI KeyDWPQODZAOSWNHB-UHFFFAOYSA-N
Description≥98% (HPLC), solid
SolubilityDMSO: >20 mg/mL
Assay≥98% (HPLC)
Colorwhite
Formsolid
Size5MG, 25MG
Storage Conditions2-8°C
1

Combined Fenobam and Amantadine Treatment Promotes Robust Antidyskinetic Effects in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned Primate Model of Parkinson's Disease

Wai Kin D Ko, Elsa Pioli, Qin Li, Steve McGuire, Audrey Dufour, Todd B Sherer, Erwan Bezard, Maurizio F Facheris

Mov Disord. 2014 May;29(6):772-9.

PMID: 24610195

1

Docking, Molecular Dynamics Simulation and Synthesis of New Fenobam Analogues as mGlu5 Receptor Antagonists

Abdollah Javidan, Mohammad Javad Taghizadeh, Seyed Ayoub Hosseini, Maryam Iman, Rahim Jafari

Comb Chem High Throughput Screen. 2016;19(9):764-770.

PMID: 27585831

1

Fenobam Promoted the Neuroprotective Effect of PEP-1-FK506BP Following Oxidative Stress by Increasing Its Transduction Efficiency

Eun Hee Ahn, Dae Won Kim, Min Jea Shin, Hyo Sang Jo, Seon Ae Eom, Duk-Soo Kim, Eun Young Park, Jong Hoon Park, Sung-Woo Cho, Jinseu Park, Won Sik Eum, Ora Son, Hyun Sook Hwang, Soo Young Choi

BMB Rep. 2013 Nov;46(11):561-6.

PMID: 24152913

1

Metabotropic Glutamate Receptor 5 Antagonism With Fenobam: Examination of Analgesic Tolerance and Side Effect Profile in Mice

Michael C Montana, Beth A Conrardy, Laura F Cavallone, Benedict J Kolber, Lesley K Rao, Suellen C Greco, Robert W Gereau 4th

Anesthesiology. 2011 Dec;115(6):1239-50.

PMID: 22037639

1

The Anxiolytic and Analgesic Properties of Fenobam, a Potent mGlu5 Receptor Antagonist, in Relation to the Impairment of Learning

Wolfgang Jacob, Andreas Gravius, Malgorzata Pietraszek, Jens Nagel, Irina Belozertseva, Elena Shekunova, Andrey Malyshkin, Sergio Greco, Caroline Barberi, Wojciech Danysz

Neuropharmacology. 2009 Aug;57(2):97-108.

PMID: 19426746

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