CAS 37951-13-6 Flavokawain A - Analytical Products / Alfa Chemistry

CAT	AP37951136
CAS	37951-13-6
Structure
Molecular Weight	314.33

Assay	≥98.0% (HPLC)
Size	20MG
Storage Conditions	2-8°C

1

Chalcone Flavokawain A Attenuates TGF-β1-induced Fibrotic Pathology via Inhibition of ROS/Smad3 Signaling Pathways and Induction of Nrf2/ARE-mediated Antioxidant Genes in Vascular Smooth Muscle Cells

You-Cheng Hseu, Ting-Yu Yang, Mei-Ling Li, Peramaiyan Rajendran, Dony Chacko Mathew, Chia-Hsuan Tsai, Ruei-Wan Lin, Chuan-Chen Lee, Hsin-Ling Yang

J Cell Mol Med. 2019 Feb;23(2):775-788.

PMID: 30549180

1

Flavokawain A Inhibits Cytochrome P450 in in Vitro Metabolic and Inhibitory Investigations

Lifeng Niu, Lina Ding, Chunyun Lu, Feifei Zuo, Ke Yao, Shaobo Xu, Wen Li, Donghua Yang, Xia Xu

J Ethnopharmacol. 2016 Sep 15;191:350-359.

PMID: 27318274

1

Flavokawain A, a Novel Chalcone From Kava Extract, Induces Apoptosis in Bladder Cancer Cells by Involvement of Bax Protein-Dependent and Mitochondria-Dependent Apoptotic Pathway and Suppresses Tumor Growth in Mice

Xiaolin Zi, Anne R Simoneau

Cancer Res. 2005 Apr 15;65(8):3479-86.

PMID: 15833884

1

In Vivo Anti-Tumor Effects of Flavokawain A in 4T1 Breast Cancer Cell-Challenged Mice

Nadiah Abu, Nurul Elyani Mohamed, Swee Keong Yeap, Kian Lam Lim, M Nadeem Akhtar, Aimi Jamil Zulfadli, Beh Boon Kee, Mohd Puad Abdullah, Abdul Rahman Omar, Noorjahan Banu Alitheen

Anticancer Agents Med Chem. 2015;15(7):905-15.

PMID: 26179368

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