Focal Adhesion Kinase Inhibitor I - CAS 4506-66-5

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For Research Use Only | Not For Clinical Use

CAT	AP4506665-B
CAS	4506-66-5
Molecular Weight	138.17

Description	The Focal Adhesion Kinase Inhibitor I, also referenced under CAS 4506-66-5, controls the biological activity of Foca Adhesion Kinase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Solubility	water: 14 mg/mL; DMSO: 50 mg/mL
Assay	≥95% (elemental analysis)
Color	gray
Form	solid; desiccated; protect from light
Size	5MG
Storage Conditions	+2C to +8C

Fluoroaluminate Stimulates Phosphorylation of p130 Cas and Fak and Increases Attachment and Spreading of Preosteoblastic MC3T3-E1 Cells

F Freitas, M Jeschke, I Majstorovic, D R Mueller, P Schindler, H Voshol, J Van Oostrum, M Susa

Bone. 2002 Jan;30(1):99-108.

PMID: 11792571

Ocular Hypotensive Efficacy of Src-family Tyrosine Kinase Inhibitors via Different Cellular Actions From Rock Inhibitors

Tomoko Kirihara, Atsushi Shimazaki, Masatsugu Nakamura, Nobuaki Miyawaki

Exp Eye Res. 2014 Feb;119:97-105.

PMID: 24321889

The Activated Insulin-Like Growth Factor I Receptor Induces Depolarization in Breast Epithelial Cells Characterized by Actin Filament Disassembly and Tyrosine Dephosphorylation of FAK, Cas, and Paxillin

M A Guvakova, E Surmacz

Exp Cell Res. 1999 Aug 25;251(1):244-55.

PMID: 10438590

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