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FPL 64176

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For Research Use Only | Not For Clinical Use
CATAP120934965
CAS120934-96-5
Structure
MDL NumberMFCD00274043
Molecular Weight347.41
InChI KeyMDMWHKZANMNXTF-UHFFFAOYSA-N
Description≥98% (HPLC), powder
SolubilityDMSO: >20 mg/mL (Solutions should be freshly prepared.); H2O: insoluble
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder; protect from light
Size25MG, 100MG
Storage Conditions2-8°C
1

Anti-schistosomal Action of the Calcium Channel Agonist FPL-64176

Paul McCusker, John D Chan

Int J Parasitol Drugs Drug Resist. 2019 Dec;11:30-38.

PMID: 31561039

1

FPL 64176 Modification of Ca(V)1.2 L-type Calcium Channels: Dissociation of Effects on Ionic Current and Gating Current

Stefan I McDonough, Yasuo Mori, Bruce P Bean

Biophys J. 2005 Jan;88(1):211-23.

PMID: 15501945

1

Kinetic Effects of FPL 64176 on L-type Ca2+ Channels in Cardiac Myocytes

J S Fan, Y Yuan, P Palade

Naunyn Schmiedebergs Arch Pharmacol. 2000 May;361(5):465-76.

PMID: 10832599

1

Molecular Determinants of the Differential Modulation of Ca v 1.2 and Ca v 1.3 by Nifedipine and FPL 64176

Yuchen Wang, Shiqi Tang, Kyle E Harvey, Amy E Salyer, T August Li, Emily K Rantz, Markus A Lill, Gregory H Hockerman

Mol Pharmacol. 2018 Sep;94(3):973-983.

PMID: 29980657

1

Pharmacological, Radioligand Binding, and Electrophysiological Characteristics of FPL 64176, a Novel Nondihydropyridine Ca2+ Channel Activator, in Cardiac and Vascular Preparations

W Zheng, D Rampe, D J Triggle

Mol Pharmacol. 1991 Nov;40(5):734-41.

PMID: 1719369

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