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FQI1

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For Research Use Only | Not For Clinical Use
CATAP599151356
CAS599151-35-6
MDL NumberMFCD03632583
Molecular Weight311.33
InChI KeyYKSYGLXHLSPWLB-UHFFFAOYSA-N
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL (clear solution)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Antiproliferative Small-Molecule Inhibitors of Transcription Factor LSF Reveal Oncogene Addiction to LSF in Hepatocellular Carcinoma

Trevor J Grant, Joshua A Bishop, Lisa M Christadore, Girish Barot, Hang Gyeong Chin, Sarah Woodson, John Kavouris, Ayesha Siddiq, Rachel Gredler, Xue-Ning Shen, Jennifer Sherman, Tracy Meehan, Kevin Fitzgerald, etc.

Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4503-8.

PMID: 22396589

1

FQI1: A Transcription-Methylation Switch for Cancer

Olga A Guryanova, Jonathan D Licht

Oncotarget. 2017 Feb 21;8(8):12536-12537.

PMID: 28177910

1

Small Molecule Inhibitors of Late SV40 Factor (LSF) Abrogate Hepatocellular Carcinoma (HCC): Evaluation Using an Endogenous HCC Model

Devaraja Rajasekaran, Ayesha Siddiq, Jennifer L S Willoughby, Jessica M Biagi, Lisa M Christadore, Sarah A Yunes, Rachel Gredler, Nidhi Jariwala, Chadia L Robertson, Maaged A Akiel, Xue-Ning Shen, Mark A Subler, etc.

Oncotarget. 2015 Sep 22;6(28):26266-77.

PMID: 26313006

1

The Transcription Factor LSF: A Novel Oncogene for Hepatocellular Carcinoma

Prasanna K Santhekadur, Devaraja Rajasekaran, Ayesha Siddiq, Rachel Gredler, Dong Chen, Scott E Schaus, Ulla Hansen, Paul B Fisher, Devanand Sarkar

Am J Cancer Res. 2012;2(3):269-85.

PMID: 22679558

1

Transcription Factor LSF-DNMT1 Complex Dissociation by FQI1 Leads to Aberrant DNA Methylation and Gene Expression

Hang Gyeong Chin, V K Chaithanya Ponnaluri, Guoqiang Zhang, Pierre-Olivier Estève, Scott E Schaus, Ulla Hansen, Sriharsa Pradhan

Oncotarget. 2016 Dec 13;7(50):83627-83640.

PMID: 27845898

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