FR194921

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For Research Use Only | Not For Clinical Use

CAT	AP202646808
CAS	202646-80-8
Structure
Molecular Weight	385.46

Description	≥98% (HPLC)
Solubility	DMSO: 2 mg/mL, clear (warmed)
Assay	≥98% (HPLC)
Color	white to beige
Form	powder
Size	5MG, 25MG
Storage Conditions	2-8°C

Design, Synthesis and Biological Evaluation of a Novel Series of Potent, Orally Active Adenosine A1 Receptor Antagonists With High Blood-Brain Barrier Permeability

S Kuroda, F Takamura, Y Tenda, H Itani, Y Tomishima, A Akahane, K Sakane

Chem Pharm Bull (Tokyo). 2001 Aug;49(8):988-98.

PMID: 11515591

Pharmacological Characterization of FR194921, a New Potent, Selective, and Orally Active Antagonist for Central Adenosine A1 Receptors

Takuya Maemoto, Miho Tada, Takuma Mihara, Noriko Ueyama, Hideaki Matsuoka, Katsuya Harada, Takayuki Yamaji, Kiyoharu Shirakawa, Satoru Kuroda, Atsushi Akahane, Akinori Iwashita, Nobuya Matsuoka, Seitaro Mutoh

J Pharmacol Sci. 2004 Sep;96(1):42-52.

PMID: 15351792

Synthesis and Evaluation of [11C]FR194921 as a Nonxanthine-Type PET Tracer for Adenosine A1 Receptors in the Brain

Takahiro Matsuya, Hiroyuki Takamatsu, Yoshihiro Murakami, Akihiro Noda, Rikiya Ichise, Yuji Awaga, Shintaro Nishimura

Nucl Med Biol. 2005 Nov;32(8):837-44.

PMID: 16253808

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