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Fraxetin

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For Research Use Only | Not For Clinical Use
CATAP574845
CAS574-84-5
Structure
MDL NumberMFCD00006873
Molecular Weight208.17
EC Number209-376-2
InChI KeyHAVWRBANWNTOJX-UHFFFAOYSA-N
Descriptionanalytical standard
Assay≥98.0% (HPLC)
Formneat; gas chromatography (GC): suitable
Gradeanalytical standard
Impurity Content≤2.5% water (calc. from elemental analysis)
MP230-231 °C (lit.)
Size50MG
1

Antifibrotic Effects of Fraxetin on Carbon Tetrachloride-Induced Liver Fibrosis by Targeting NF-κB/IκBα, MAPKs and Bcl-2/Bax Pathways

Bin Wu, Rong Wang, Shengnan Li, Yuanyuan Wang, Fuxing Song, Yanqiu Gu, Yongfang Yuan

Pharmacol Rep. 2019 Jun;71(3):409-416.

PMID: 31003150

1

Effect of Fraxetin on Proliferation and Apoptosis in Breast Cancer Cells

Guodong Liu, Zhenfang Liu, Yuexiang Yan, Haiyan Wang

Oncol Lett. 2017 Dec;14(6):7374-7378.

PMID: 29344176

1

Fraxetin Induces Heme Oxygenase-1 Expression by Activation of Akt/Nrf2 or AMP-activated Protein Kinase α/Nrf2 Pathway in HaCaT Cells

Juthika Kundu, In Gyeong Chae, Kyung-Soo Chun

J Cancer Prev. 2016 Sep;21(3):135-143.

PMID: 27722139

1

Inhibition of Osteoclastogenesis for Periprosthetic Osteolysis Therapy Through the Suppression of p38 Signaling by Fraxetin

Jia-Cheng Liao, Zhao-Xia Wei, Chang Zhao, Zhong-Ping Ma, Dao-Zhang Cai

Int J Mol Med. 2018 Sep;42(3):1257-1264.

PMID: 29786751

1

The Therapeutic Effect of Fraxetin on Ethanol-Induced Hepatic Fibrosis by Enhancing Ethanol Metabolism, Inhibiting Oxidative Stress and Modulating Inflammatory Mediators in Rats

Xiaowei Chen, Xiaozhou Ying, Weiming Sun, Huijia Zhu, Xin Jiang, Bin Chen

Int Immunopharmacol. 2018 Mar;56:98-104.

PMID: 29414667

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