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FTI-277 trifluoroacetate salt

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For Research Use Only | Not For Clinical Use
CATALP170006732
CAS170006-73-2 (free base)
MDL NumberMFCD06795840
Molecular Weight447.61 (free base basis)
InChI KeyGJEFFRDWFVSCOJ-PXPMWPIZSA-N
Description≥95% (HPLC), film
SolubilityH2O: ≥2 mg/mL
Assay≥95% (HPLC)
Formfilm
Size1MG, 5MG
Storage Conditions−70°C
1

Farnesyltransferase Inhibitor FTI-277 Reduces Mortality of Septic Mice Along With Improved Bacterial Clearance

Wen Yang, Marina Yamada, Yoshiaki Tamura, Kyungho Chang, Ji Mao, Lin Zou, Yan Feng, Kotaro Kida, Marielle Scherrer-Crosbie, Wei Chao, Fumito Ichinose, Yong-Ming Yu, Alan J Fischman, Ronald G Tompkins, Shanglong Yao, etc.

J Pharmacol Exp Ther. 2011 Dec;339(3):832-41.

PMID: 21873557

1

Tipifarnib-induced Apoptosis in Acute Myeloid Leukemia and Multiple Myeloma Cells Depends on Ca2+ Influx Through Plasma Membrane Ca2+ Channels

Niranjan Yanamandra, Robert W Buzzeo, Mark Gabriel, Lori A Hazlehurst, Yelenis Mari, Darrin M Beaupre, Javier Cuevas

J Pharmacol Exp Ther. 2011 Jun;337(3):636-43.

PMID: 21378206

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