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GANT61

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For Research Use Only | Not For Clinical Use
CATAP500579044
CAS500579-04-4
Molecular Weight429.60
Description≥98% (HPLC)
SolubilityDMSO: >2 mg/mL
Assay≥98% (HPLC)
Colorwhite to off-white
Formpowder
Size5MG, 25MG
1

Chemical, Computational and Functional Insights Into the Chemical Stability of the Hedgehog Pathway Inhibitor GANT61

Andrea Calcaterra, Valentina Iovine, Bruno Botta, Deborah Quaglio, Ilaria D'Acquarica, Alessia Ciogli, Antonia Iazzetti, Romina Alfonsi, Ludovica Lospinoso Severini, Paola Infante, Lucia Di Marcotullio, etc.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):349-358.

PMID: 29338454

1

Concomitant Targeting of Hedgehog Signaling and MCL-1 Synergistically Induces Cell Death in Hedgehog-driven Cancer Cells

Michael Torsten Meister, Cathinka Boedicker, Benedikt Linder, Donat Kögel, Thomas Klingebiel, Simone Fulda

Cancer Lett. 2019 Nov 28;465:1-11.

PMID: 31465840

1

GANT61 Alleviates Arthritic Symptoms by Targeting Fibroblast-Like Synoviocytes in CIA Rats

Suping Qin, Dexu Sun, Xiangyang Li, Fanyun Kong, Qian Yu, Hui Hua, Kuiyang Zheng, Renxian Tang

J Orthop Sci. 2019 Mar;24(2):353-360.

PMID: 30268354

1

Temporal and Partial Inhibition of GLI1 in Neural Stem Cells (NSCs) Results in the Early Maturation of NSC Derived Oligodendrocytes in Vitro

Poommaree Namchaiw, Han Wen, Florian Mayrhofer, Olga Chechneva, Sangita Biswas, Wenbin Deng

Stem Cell Res Ther. 2019 Aug 27;10(1):272.

PMID: 31455382

1

The Hedgehog Signaling Pathway: A Viable Target in Breast Cancer?

Priyanka Bhateja, Mathew Cherian, Sarmila Majumder, Bhuvaneswari Ramaswamy

Cancers (Basel). 2019 Aug 7;11(8):1126.

PMID: 31394751

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