CAS 11021-13-9 Ginsenoside Rb2 - Analytical Products / Alfa Chemistry

CAT	AP11021139-A
CAS	11021-13-9
Structure
MDL Number	MFCD00221755
Synonyms	Ginsenoside Rb2, (3β,12β)-20-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside,β-D-Glucopyranoside, (3β,12β)-20-[(6-O-α-L-arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-, Dammarane, β-D-glucopyranoside deriv., NSC 308878, Ginsenoside C
IUPAC Name	(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular Weight	1079.27
Molecular Formula	C53H90O22
EC Number	234-251-4
Canonical SMILES	CC(=CCC[C@](C)(O[C@@H]1O[C@H](CO[C@@H]2OC[C@H](O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O)[C@H]3CC[C@]4(C)[C@@H]3[C@H](O)C[C@@H]5[C@@]6(C)CC[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)C(C)(C)[C@@H]6CC[C@@]45C)C
InChI	InChI=1S/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-69-45-41(65)34(58)26(57)21-68-45)24-11-16-52(7)33(24)25(56)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)36(60)28(20-55)71-48)74-46-42(66)38(62)35(59)27(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3/t24-,25+,26-,27+,28+,29+,30-,31+,32-,33-,34-,35+,36+,37+,38-,39-,40-,41+,42+,43+,44+,45-,46-,47-,48-,50-,51+,52+,53-/m0/s1
InChI Key	NODILNFGTFIURN-GZPRDHCNSA-N

Description	analytical standard
Accurate Mass	1078.5924
Assay	≥95.0% (HPLC); ≥90.0% (HPLC)
Form	neat; gas chromatography (GC): suitable
Format	Neat
Grade	analytical standard
Shipping	Room Temperature
Size	10MG
Storage Conditions	2-8°C
Subcategory	Oligosaccharides

1

Ginsenoside Rb2 Alleviates Obesity by Activation of Brown Fat and Induction of Browning of White Fat

Yilian Hong, Yi Lin, Qiya Si, Lijuan Yang, Weisong Dong, Xuejiang Gu

Front Endocrinol (Lausanne). 2019 Mar 15;10:153.

PMID: 30930854

1

Ginsenoside Rb2 Inhibits Epithelial-Mesenchymal Transition of Colorectal Cancer Cells by Suppressing TGF-β/Smad Signaling

Guoliang Dai, Bingting Sun, Tao Gong, Zihao Pan, Qinghai Meng, Wenzheng Ju

Phytomedicine. 2019 Mar 15;56:126-135.

PMID: 30668333

1

Ginsenoside Rb2 Suppresses the Glutamate-Mediated Oxidative Stress and Neuronal Cell Death in HT22 Cells

Dong Hoi Kim, Dae Won Kim, Bo Hyun Jung, Jong Hun Lee, Heesu Lee, Gwi Seo Hwang, Ki Sung Kang, Jae Wook Lee

J Ginseng Res. 2019 Apr;43(2):326-334.

PMID: 30976171

1

Ginsenoside-Rb2 and 20(S)-Ginsenoside-Rg3 From Korean Red Ginseng Prevent Rotavirus Infection in Newborn Mice

Hui Yang, Kwang-Hoon Oh, Hyun Jin Kim, Young Ho Cho, Yung Choon Yoo

J Microbiol Biotechnol. 2018 Mar 28;28(3):391-396.

PMID: 29316736

1

The Anti-Metastatic Effect of Ginsenoside Rb2 in Colorectal Cancer in an EGFR/SOX2-dependent Manner

Lan Thi Hanh Phi, Yoseph Toni Wijaya, Ita Novita Sari, Ying-Gui Yang, Yun Kyung Lee, Hyog Young Kwon

Cancer Med. 2018 Nov;7(11):5621-5631.

PMID: 30264477

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