CAS 303-45-7 (±)-Gossypol from cotton seeds - Analytical Products / Alfa Chemistry

CAT	AP303457-B
CAS	303-45-7
MDL Number	MFCD00017352
Molecular Weight	518.55
InChI Key	QBKSWRVVCFFDOT-UHFFFAOYSA-N

Description	≥95% (HPLC)
Assay	≥95% (HPLC)
Size	100MG, 250MG
Storage Conditions	2-8°C

1

A Novel Role of the Mitochondrial Permeability Transition Pore in (-)-Gossypol-Induced Mitochondrial Dysfunction

Verena Warnsmann, Nina Meyer, Andrea Hamann, Donat Kögel, Heinz D Osiewacz

Mech Ageing Dev. 2018 Mar;170:45-58.

PMID: 28684269

1

AT 101 Induces Early Mitochondrial Dysfunction and HMOX1 (Heme Oxygenase 1) to Trigger Mitophagic Cell Death in Glioma Cells

Nina Meyer, Svenja Zielke, Jonas B Michaelis, Benedikt Linder, Verena Warnsmann, Stefanie Rakel, Heinz D Osiewacz, Simone Fulda, Michel Mittelbronn, Christian Münch, Christian Behrends, Donat Kögel

Autophagy. 2018;14(10):1693-1709.

PMID: 29938581

1

Gossypol Induces Disruption of Spermatogenesis and Steroidogenesis in Male Mice

Whasun Lim, Jiyeon Ham, Sunwoo Park, Hyocheol Bae, Seungkwon You, Gwonhwa Song

J Agric Food Chem. 2019 Feb 20;67(7):2075-2085.

PMID: 30678458

1

Gossypol Inhibits 5α-reductase 1 and 3α-hydroxysteroid Dehydrogenase: Its Possible Use for the Treatment of Prostate Cancer

Shuyan Cao, Guimin Wang, Fei Ge, Xiaoheng Li, Qiqi Zhu, Ren-Shan Ge, Yunshan Wang

Fitoterapia. 2019 Mar;133:102-108.

PMID: 30605780

1

Toxicity of Gossypol From Cottonseed Cake to Sheep Ovarian Follicles

Antônio Carlos Lopes Câmara, Ivana Cristina Nunes Gadelha, Pedro Augusto Cordeiro Borges, Silvano Alves de Paiva, Marília Martins Melo, Benito Soto-Blanco

PLoS One. 2015 Nov 24;10(11):e0143708.

PMID: 26600470

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