Granzyme B Inhibitor IV

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For Research Use Only | Not For Clinical Use

CAT	IAR42415435
Molecular Weight	498.53

Description	The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.
Solubility	DMSO: 5 mg/mL
Assay	≥97% (HPLC)
Color	white
Form	solid
Size	1MG
Storage Conditions	-20C

[The Serine Proteases and Their Function in Neuronal Death Processes]

O Fuster Lluch, M F Galindo, V Ceña, J Jordán

Rev Neurol. 2004 Mar 1-15;38(5):449-57.

PMID: 15029525

Differential Suppression by Protease Inhibitors and Cytokines of Apoptosis Induced by Wild-Type p53 and Cytotoxic Agents

J Lotem, L Sachs

Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12507-12.

PMID: 8901612

Expression of the Apoptosis Inhibitor Protease Inhibitor 9 Predicts Clinical Outcome in Vaccinated Patients With Stage III and IV Melanoma

Inge S van Houdt, Joost J Oudejans, Alfonsus J M van den Eertwegh, Arnold Baars, Wim Vos, Bellinda A Bladergroen, Donata Rimoldi, Jettie J F Muris, Erik Hooijberg, Chad M Gundy, Chris J L M Meijer, Jean A Kummer

Clin Cancer Res. 2005 Sep 1;11(17):6400-7.

PMID: 16144945

Selective BRAF Inhibitors Induce Marked T-cell Infiltration Into Human Metastatic Melanoma

James S Wilmott, Georgina V Long, Julie R Howle, Lauren E Haydu, Raghwa N Sharma, John F Thompson, Richard F Kefford, Peter Hersey, Richard A Scolyer

Clin Cancer Res. 2012 Mar 1;18(5):1386-94.

PMID: 22156613

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