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GSK1210151A

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For Research Use Only | Not For Clinical Use
CATAP1300031495
CAS1300031-49-5
Molecular Weight415.44
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

BET Inhibition Improves NASH and Liver Fibrosis

Sarah A Middleton, Neetu Rajpal, Leanne Cutler, Palwinder Mander, Inmaculada Rioja, Rab K Prinjha, Deepak Rajpal, Pankaj Agarwal, Vinod Kumar

Sci Rep. 2018 Nov 22;8(1):17257.

PMID: 30467325

1

BRD4 Is Associated With Raccoon Polyomavirus Genome and Mediates Viral Gene Transcription and Maintenance of a Stem Cell State in Neuroglial Tumour Cells

Molly E Church, Marko Estrada, Christian M Leutenegger, Florante N Dela Cruz, Patricia A Pesavento, Kevin D Woolard

J Gen Virol. 2016 Nov;97(11):2939-2948.

PMID: 27600312

1

Identification of a Novel Series of BET Family Bromodomain Inhibitors: Binding Mode and Profile of I-BET151 (GSK1210151A)

Jonathan Seal, Yann Lamotte, Frédéric Donche, Anne Bouillot, Olivier Mirguet, Françoise Gellibert, Edwige Nicodeme, Gael Krysa, Jorge Kirilovsky, Soren Beinke, Scott McCleary, Inma Rioja, Paul Bamborough, etc.

Bioorg Med Chem Lett. 2012 Apr 15;22(8):2968-72.

PMID: 22437115

1

Inhibition of BET Recruitment to Chromatin as an Effective Treatment for MLL-fusion Leukaemia

Mark A Dawson, Rab K Prinjha, Antje Dittmann, George Giotopoulos, Marcus Bantscheff, Wai-In Chan, Samuel C Robson, Chun-wa Chung, Carsten Hopf, Mikhail M Savitski, Carola Huthmacher, Emma Gudgin, Dave Lugo, etc.

Nature. 2011 Oct 2;478(7370):529-33.

PMID: 21964340

1

Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC)

Jonathan Welti, Adam Sharp, Wei Yuan, David Dolling, Daniel Nava Rodrigues, Ines Figueiredo, Veronica Gil, Antje Neeb, Matthew Clarke, George Seed, Mateus Crespo, Semini Sumanasuriya, Jian Ning, Eleanor Knight, etc.

Clin Cancer Res. 2018 Jul 1;24(13):3149-3162.

PMID: 29555663

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