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GSK2194069

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For Research Use Only | Not For Clinical Use
CATAP1332331084
CAS1332331-08-4
MDL NumberMFCD28167807
Molecular Weight428.48
InChI KeyAQTPWCUIYUOEMG-INIZCTEOSA-N
Description≥97% (HPLC)
SolubilityDMSO: 5 mg/mL, clear (warmed)
Assay≥97% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A Human Fatty Acid Synthase Inhibitor Binds β-ketoacyl Reductase in the Keto-Substrate Site

Mary Ann Hardwicke, Alan R Rendina, Shawn P Williams, Michael L Moore, Liping Wang, Julie A Krueger, Ramona N Plant, Rachel D Totoritis, Guofeng Zhang, Jacques Briand, William A Burkhart, Kristin K Brown, etc.

Nat Chem Biol. 2014 Sep;10(9):774-9.

PMID: 25086508

1

Molecular Pathways: Fatty Acid Synthase

Suzanne F Jones, Jeffrey R Infante

Clin Cancer Res. 2015 Dec 15;21(24):5434-8.

PMID: 26519059

1

Toll-like Receptor Mediated Inflammation Requires FASN-dependent MYD88 Palmitoylation

Young-Chan Kim, Sang Eun Lee, Somi K Kim, Hyun-Duk Jang, Injoo Hwang, Sooryeonhwa Jin, Eun-Byeol Hong, Kyoung-Soon Jang, Hyo-Soo Kim

Nat Chem Biol. 2019 Sep;15(9):907-916.

PMID: 31427815

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