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GSK2334470

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For Research Use Only | Not For Clinical Use
CATAP1227911456
CAS1227911-45-6
MDL NumberMFCD21608525
Molecular Weight462.59
InChI KeyQLPHOXTXAKOFMU-WBVHZDCISA-N
Description≥98% (HPLC)
SolubilityDMSO: ≥10 mg/mL
Assay≥98% (HPLC)
Colorwhite to light brown
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Characterization of GSK2334470, a Novel and Highly Specific Inhibitor of PDK1

Ayaz Najafov, Eeva M Sommer, Jeffrey M Axten, M Phillip Deyoung, Dario R Alessi

Biochem J. 2011 Jan 15;433(2):357-69.

PMID: 21087210

1

Effects of Intracellular Iron Overload on Cell Death and Identification of Potent Cell Death Inhibitors

Shenglin Fang, Xiaonan Yu, Haoxuan Ding, Jianan Han, Jie Feng

Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303.

PMID: 29890135

1

IGF-1 Protects SH-SY5Y Cells Against MPP

Chanyang Kim, Seungjoon Park

Endocr Connect. 2018 Mar;7(3):443-455.

PMID: 29459421

1

Kinome-Wide RNA Interference Screen Reveals a Role for PDK1 in Acquired Resistance to CDK4/6 Inhibition in ER-Positive Breast Cancer

Valerie M Jansen, Neil E Bhola, Joshua A Bauer, Luigi Formisano, Kyung-Min Lee, Katherine E Hutchinson, Agnieszka K Witkiewicz, Preston D Moore, Mónica Valéria Estrada, Violeta Sánchez, Paula G Ericsson, etc.

Cancer Res. 2017 May 1;77(9):2488-2499.

PMID: 28249908

1

PI3Kδ Inhibitor Idelalisib in Combination With BTK Inhibitor ONO/GS-4059 in Diffuse Large B Cell Lymphoma With Acquired Resistance to PI3Kδ and BTK Inhibitors

Anella Yahiaoui, Sarah A Meadows, Rick A Sorensen, Zhi-Hua Cui, Kathleen S Keegan, Robert Brockett, Guang Chen, Christophe Quéva, Li Li, Stacey L Tannheimer

PLoS One. 2017 Feb 8;12(2):e0171221.

PMID: 28178345

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