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GSK583

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For Research Use Only | Not For Clinical Use
CATAP1346547009
CAS1346547-00-9
Molecular Weight398.45
Description≥98% (HPLC)
SolubilityDMSO: 20 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder; protect from light
Size5MG, 25MG
Storage Conditions2-8°C
1

Identification of Quinoline-Based RIP2 Kinase Inhibitors With an Improved Therapeutic Index to the hERG Ion Channel

Pamela A Haile, Linda N Casillas, Michael J Bury, John F Mehlmann, Robert Singhaus Jr, Adam K Charnley, Terry V Hughes, Michael P DeMartino, Gren Z Wang, Joseph J Romano, Xiaoyang Dong, Nikolay V Plotnikov, etc.

ACS Med Chem Lett. 2018 Sep 26;9(10):1039-1044.

PMID: 30344914

1

The Identification and Pharmacological Characterization of 6-(tert-Butylsulfonyl)-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine (GSK583), a Highly Potent and Selective Inhibitor of RIP2 Kinase

Pamela A Haile, Bartholomew J Votta, Robert W Marquis, Michael J Bury, John F Mehlmann, Robert Singhaus Jr, Adam K Charnley, Ami S Lakdawala, Máire A Convery, David B Lipshutz, Biva M Desai, Barbara Swift, etc.

J Med Chem. 2016 May 26;59(10):4867-80.

PMID: 27109867

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