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GSK690693

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For Research Use Only | Not For Clinical Use
CATAP937174760
CAS937174-76-0
Structure
MDL NumberMFCD14105605
Molecular Weight425.48
InChI KeyKGPGFQWBCSZGEL-ZDUSSCGKSA-N
Description≥98% (HPLC)
SolubilityDMSO: 5 mg/mL (clear solution)
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

Augmenting the Therapeutic Efficacy of Adenosine Against Pancreatic Cancer by Switching the Akt/p21-dependent Senescence to Apoptosis

Dongqin Yang, Qi Zhang, Yunfang Ma, Zhihui Che, Wenli Zhang, Mengmeng Wu, Lijun Wu, Fuchen Liu, Yiwei Chu, Wei Xu, Mary McGrath, Chunhua Song, Jie Liu

EBioMedicine. 2019 Sep;47:114-127.

PMID: 31495718

1

Causal Reasoning Identifies Mechanisms of Sensitivity for a Novel AKT Kinase Inhibitor, GSK690693

Rakesh Kumar, Stephen J Blakemore, Catherine E Ellis, Emanuel F Petricoin 3rd, Dexter Pratt, Michael Macoritto, Andrea L Matthews, Joseph J Loureiro, Keith Elliston

BMC Genomics. 2010 Jul 6;11:419.

PMID: 20604938

1

Characterization of an Akt Kinase Inhibitor With Potent Pharmacodynamic and Antitumor Activity

Nelson Rhodes, Dirk A Heerding, Derek R Duckett, Derek J Eberwein, Victoria B Knick, Timothy J Lansing, Randy T McConnell, Tona M Gilmer, Shu-Yun Zhang, Kimberly Robell, Jason A Kahana, Robert S Geske, etc.

Cancer Res. 2008 Apr 1;68(7):2366-74.

PMID: 18381444

1

GSK690693 Delays Tumor Onset and Progression in Genetically Defined Mouse Models Expressing Activated Akt

Deborah A Altomare, Lili Zhang, Jing Deng, Antonio Di Cristofano, Andres J Klein-Szanto, Rakesh Kumar, Joseph R Testa

Clin Cancer Res. 2010 Jan 15;16(2):486-96.

PMID: 20075391

1

Mechanism and Management of AKT Inhibitor-Induced Hyperglycemia

Ming-Chih Crouthamel, Jason A Kahana, Susan Korenchuk, Shu-Yun Zhang, Gobalakrishnan Sundaresan, Derek J Eberwein, Kathleen K Brown, Rakesh Kumar

Clin Cancer Res. 2009 Jan 1;15(1):217-25.

PMID: 19118049

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