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GSK837149A

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For Research Use Only | Not For Clinical Use
CATAP13616290
CAS13616-29-0
Molecular Weight554.60
Description≥98% (HPLC), solid
SolubilityDMSO: >10 mg/mL; H2O: insoluble
Assay≥98% (HPLC)
Colorwhite to off-white
Formsolid
Size5MG, 25MG
Storage Conditions2-8°C
1

Discovery of GSK837149A, an Inhibitor of Human Fatty Acid Synthase Targeting the Beta-Ketoacyl Reductase Reaction

María Jesús Vázquez, William Leavens, Ronggang Liu, Beatriz Rodríguez, Martin Read, Stephen Richards, Deborah Winegar, Juan Manuel Domínguez

FEBS J. 2008 Apr;275(7):1556-67.

PMID: 18312417

1

Evaluation of FASN Inhibitors by a Versatile Toolkit Reveals Differences in Pharmacology Between Human and Rodent FASN Preparations and in Antiproliferative Efficacy in Vitro vs. In Situ in Human Cancer Cells

Prosanta K Singha, Kiira Mäklin, Taina Vihavainen, Tuomo Laitinen, Tapio J Nevalainen, Mahadeo R Patil, Arun K Tonduru, Antti Poso, Jarmo T Laitinen, Juha R Savinainen

Eur J Pharm Sci. 2020 Apr 7;149:105321.

PMID: 32275951

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