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GSK983

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For Research Use Only | Not For Clinical Use
CATAP827591026
CAS827591-02-6
MDL NumberMFCD28978021
Molecular Weight325.79
Description≥98% (HPLC)
SolubilityDMSO: 10 mg/mL, clear
Assay≥98% (HPLC)
Colorwhite to beige
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

A High Throughput Screen Identifies Benzoquinoline Compounds as Inhibitors of Ebola Virus Replication

Priya Luthra, Jue Liang, Colette A Pietzsch, Sudip Khadka, Megan R Edwards, Shuguang Wei, Sampriti De, Bruce Posner, Alexander Bukreyev, Joseph M Ready, Christopher F Basler

Antiviral Res. 2018 Feb;150:193-201.

PMID: 29294299

1

Discovery of Small Molecule Inhibitors of Human Uridine-Cytidine Kinase 2 by High-Throughput Screening

Ayse Okesli-Armlovich, Amita Gupta, Marta Jimenez, Douglas Auld, Qi Liu, Michael C Bassik, Chaitan Khosla

Bioorg Med Chem Lett. 2019 Sep 15;29(18):2559-2564.

PMID: 31420268

1

Enhancing the Antiviral Efficacy of RNA-Dependent RNA Polymerase Inhibition by Combination With Modulators of Pyrimidine Metabolism

Qi Liu, Amita Gupta, Ayse Okesli-Armlovich, Wenjie Qiao, Curt R Fischer, Mark Smith, Jan E Carette, Michael C Bassik, Chaitan Khosla

Cell Chem Biol. 2020 Jun 18;27(6):668-677.e9.

PMID: 32442424

1

Inhibiting Pyrimidine Biosynthesis Impairs Ebola Virus Replication Through Depletion of Nucleoside Pools and Activation of Innate Immune Responses

Priya Luthra, Jacinth Naidoo, Colette A Pietzsch, Sampriti De, Sudip Khadka, Manu Anantpadma, Caroline G Williams, Megan R Edwards, Robert A Davey, Alexander Bukreyev, Joseph M Ready, Christopher F Basler

Antiviral Res. 2018 Oct;158:288-302.

PMID: 30144461

1

Parallel shRNA and CRISPR-Cas9 Screens Enable Antiviral Drug Target Identification

Richard M Deans, David W Morgens, Ayşe Ökesli, Sirika Pillay, Max A Horlbeck, Martin Kampmann, Luke A Gilbert, Amy Li, Roberto Mateo, Mark Smith, Jeffrey S Glenn, Jan E Carette, Chaitan Khosla, Michael C Bassik

Nat Chem Biol. 2016 May;12(5):361-6.

PMID: 27018887

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