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GTS-21

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For Research Use Only | Not For Clinical Use
CATAP156223051
CAS156223-05-1
Structure
MDL NumberMFCD00941364
Molecular Weight381.30
InChI KeyBXKYFUGAAFLYJL-BXGYHSFXSA-N
Description≥97% (HPLC)
SolubilityH2O: >5 mg/mL
Assay≥97% (HPLC)
Colorfaintly yellow to dark yellow
Formpowder
Size5MG, 25MG
Storage Conditions2-8°C
1

GTS-21 Attenuates Loss of Body Mass, Muscle Mass, and Function in Rats Having Systemic Inflammation With and Without Disuse Atrophy

Stefan J Schaller, Michio Nagashima, Martin Schönfelder, Tomoki Sasakawa, Fabian Schulz, Mohammed A S Khan, William R Kem, Gerhard Schneider, Jürgen Schlegel, Heidrun Lewald, Manfred Blobner, J A Jeevendra Martyn

Pflugers Arch. 2018 Nov;470(11):1647-1657.

PMID: 30006848

1

GTS-21 Has Cell-Specific Anti-Inflammatory Effects Independent of α7 Nicotinic Acetylcholine Receptors

Brijesh K Garg, Ralph H Loring

PLoS One. 2019 Apr 4;14(4):e0214942.

PMID: 30947238

1

GTS-21 Protected Against LPS-Induced Sepsis Myocardial Injury in Mice Through α7nAChR

Weilan Kong, Kai Kang, Yang Gao, Haitao Liu, Xianglin Meng, Yanhui Cao, Songliu Yang, Wen Liu, Jiannan Zhang, Kaijiang Yu, Mingyan Zhao

Inflammation. 2018 Jun;41(3):1073-1083.

PMID: 29680908

1

GTS-21 Reduces Inflammation in Acute Lung Injury by Regulating M1 Polarization and Function of Alveolar Macrophages

Jing Wang, Ruiting Li, Zhiyong Peng, Wenhai Zhou, Bo Hu, Xin Rao, Xiao Yang, Jianguo Li

Shock. 2019 Mar;51(3):389-400.

PMID: 29608552

1

GTS-21 Reduces Microvascular Permeability During Experimental Endotoxemia

Karsten Schmidt, Sukanya Bhakdisongkhram, Florian Uhle, Christoph Philipsenburg, Aleksandar R Zivkovic, Thorsten Brenner, Johann Motsch, Markus A Weigand, Stefan Hofer

Microvasc Res. 2018 Jan;115:75-82.

PMID: 28818494

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