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Guggulsterone Z

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For Research Use Only | Not For Clinical Use
CATAP39025235-A
CAS39025-23-5
Structure
MDL NumberMFCD01310757
Molecular Weight312.45
InChI KeyWDXRGPWQVHZTQJ-OSJVMJFVSA-N
DescriptionUnited States Pharmacopeia (USP) Reference Standard
Size25MG
1

Guggulsterone Inhibits Human Cholangiocarcinoma Sk-ChA-1 and Mz-ChA-1 Cell Growth by Inducing Caspase-Dependent Apoptosis and Downregulation of Survivin and Bcl-2 Expression

Fei Zhong, Jing Yang, Zhu-Ting Tong, Liu-Liu Chen, Lu-Lu Fan, Fang Wang, Xia-Li Zha, Jun Li

Oncol Lett. 2015 Sep;10(3):1416-1422.

PMID: 26622683

1

Synthesis and Inhibitory Effect of Cis-Guggulsterone on Lipopolysaccharide-Induced Production of Nitric Oxide in Macrophages

Jun Yeon Park, Jae Wook Lee, Chang-Ho Lee, Hae-Jeung Lee, Ki Sung Kang

Bioorg Med Chem Lett. 2020 Mar 1;30(5):126962.

PMID: 31980338

1

Targeting Beta-Catenin Signaling to Induce Apoptosis in Human Breast Cancer Cells by Z-Guggulsterone and Gugulipid Extract of Ayurvedic Medicine Plant Commiphora Mukul

Guoqin Jiang, Xiao Xiao, Yan Zeng, Kalyanam Nagabhushanam, Muhammed Majeed, Dong Xiao

BMC Complement Altern Med. 2013 Aug 3;13:203.

PMID: 23914993

1

Z-Guggulsterone Attenuates Astrocytes-Mediated Neuroinflammation After Ischemia by Inhibiting Toll-Like Receptor 4 Pathway

Tianlong Liu, Minna Liu, Tiejun Zhang, Wenxing Liu, Hang Xu, Fei Mu, Danjun Ren, Na Jia, Zhengjun Li, Yi Ding, Aidong Wen, Yuwen Li

J Neurochem. 2018 Dec;147(6):803-815.

PMID: 30168601

1

Z-Guggulsterone Attenuates Glucocorticoid-Induced Osteoporosis Through Activation of Nrf2/HO-1 Signaling

Yier Xu, Jian Guan, Jianyu Xu, Shuilin Chen, Guicai Sun

Life Sci. 2019 May 1;224:58-66.

PMID: 30905781

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