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GW4869

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For Research Use Only | Not For Clinical Use
CATAP6823694
CAS6823-69-4
Molecular Weight577.50
InChI KeyNSFKAZDTKIKLKT-LOLTXFFGSA-N
Description≥90% (NMR)
SolubilityDMSO: 0.2 mg/mL; GlaxoSmithKline
Assay≥90% (NMR)
Colorlight yellow to yellow
Formpowder; protect from light
MP>300 °C
Size5MG, 25MG
Storage Conditions2-8°C
1

Blockade of Exosome Generation With GW4869 Dampens the Sepsis-Induced Inflammation and Cardiac Dysfunction

Kobina Essandoh, Liwang Yang, Xiaohong Wang, Wei Huang, Dongze Qin, Jiukuan Hao, Yigang Wang, Basilia Zingarelli, Tianqing Peng, Guo-Chang Fan

Biochim Biophys Acta. 2015 Nov;1852(11):2362-71.

PMID: 26300484

1

Cancer-associated Fibroblast Exosomes Regulate Survival and Proliferation of Pancreatic Cancer Cells

K E Richards, A E Zeleniak, M L Fishel, J Wu, L E Littlepage, R Hill

Oncogene. 2017 Mar 30;36(13):1770-1778.

PMID: 27669441

1

Engineered Exosomes as Vehicles for Biologically Active Proteins

Ulrich Sterzenbach, Ulrich Putz, Ley-Hian Low, John Silke, Seong-Seng Tan, Jason Howitt

Mol Ther. 2017 Jun 7;25(6):1269-1278.

PMID: 28412169

1

Inhibiting Extracellular Vesicles Formation and Release: A Review of EV Inhibitors

Mariadelva Catalano, Lorraine O'Driscoll

J Extracell Vesicles. 2019 Dec 19;9(1):1703244.

PMID: 32002167

1

Involvement of Macrophage-Derived Exosomes in Abdominal Aortic Aneurysms Development

Yidong Wang, Liangliang Jia, Yao Xie, Zhejun Cai, Zhenjie Liu, Jian Shen, Yi Lu, Yaping Wang, Shengan Su, Yuankun Ma, Meixiang Xiang

Atherosclerosis. 2019 Oct;289:64-72.

PMID: 31479773

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